Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11433313 | 0.79 | HDAC3 (0.38) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL12548837 | 0.77 | HDAC3 (0.40) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL1549986 | 0.76 | ALDH1A1 (0.40) | ALDH1A1HSD17B10 | |
| SCHEMBL918555 | 0.73 | CYP1A2 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL19227482 | 0.73 | — | — | |
| SCHEMBL29953117 | 0.72 | — | — | |
| SCHEMBL31539134 | 0.72 | EPHX1 (0.45) | HDAC11ALDH1A1HSD17B10 | |
| SCHEMBL2362720 | 0.71 | HDAC3 (0.30) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL180793 | 0.71 | EPHX1 (0.36) | ALDH1A1HSD17B10 | |
| SCHEMBL11444351 | 0.70 | TSHR (0.34) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8569441-B2 | Process for transforming the end groups of polymers | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2013-10-29 | — | — | US | disclosed |
| US-20100137548-A1 | PROCESS FOR TRANSFORMING THE END GROUPS OF POLYMERS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2010-06-03 | — | — | US | disclosed |
| EP-2132235-A1 | PROCESS FOR TRANSFORMING THE END GROUPS OF POLYMERS | Commonwealth Scientific and Industrial Research Organisation (AU) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008103144-A1 | PROCESS FOR TRANSFORMING THE END GROUPS OF POLYMERS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2008-08-28 | — | — | WO | disclosed |