SCHEMBL180793

SCHEMBL180793

CCCCSC(=S)SC(C)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.36
ALDH1A1 P00352 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
NOS3 P29474 1/20 0.34
NOS1 P29475 1/20 0.34
NOS2 P35228 1/20 0.34
ACE2 Q9BYF1 1/20 0.33
CA2 P00918 1/20 0.33
MAPK1 P28482 1/20 0.33
GPR84 Q9NQS5 3/20 0.32
FFAR1 O14842 1/20 0.32
ACHE P22303 3/20 0.32
MAPT P10636 2/20 0.32
GMNN O75496 1/20 0.32
TP53 P04637 1/20 0.32
POLB P06746 1/20 0.32
THRB P10828 1/20 0.32
CYP2C9 P11712 1/20 0.32
BLM P54132 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL181033 0.93 EPHX1 (0.45) EPHX1ALDH1A1ACE2GPR84FFAR1
SCHEMBL31539134 0.93 EPHX1 (0.45) EPHX1ALDH1A1ACE2GPR84FFAR1
SCHEMBL3088096 0.84 EPHX1 (0.50) EPHX1ALDH1A1NPSR1NOS3NOS1
SCHEMBL3714955 0.81 CA1 (0.39) EPHX1ALDH1A1NPSR1NOS3NOS1
SCHEMBL12548837 0.81 HDAC3 (0.40) ALDH1A1HSD17B10
SCHEMBL16866707 0.80 ACHE (0.35) EPHX1ALDH1A1NPSR1NOS3NOS1
SCHEMBL918555 0.80 CYP1A2 (0.47) ALDH1A1HSD17B10LMNA
SCHEMBL20387804 0.79 NOS3 (0.40) ALDH1A1NPSR1NOS3NOS1NOS2
SCHEMBL3077932 0.78 GPR84 (0.35) ALDH1A1NPSR1NOS3NOS1NOS2
SCHEMBL16870483 0.78 ACHE (0.37) EPHX1ALDH1A1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12371375-B2 Cement slurries, cured cement and methods of making and use of these SAUDI ARABIAN OIL COMPANY (SA) 2025-07-29 US claimed
CN-117141062-B Flame-retardant copper-clad plate and preparation process thereof 江苏富乐华半导体科技股份有限公司 2024-03-15 CN claimed
CN-117141062-A Flame-retardant copper-clad plate and preparation process thereof 江苏富乐华半导体科技股份有限公司 2023-12-01 CN claimed
EP-4217106-A1 IMPROVEMENTS IN LIQUID CHROMATOGRAPHY SUBSTRATES University Of South Australia (AU) 2023-08-02 EP claimed
CN-114917411-A Mixed gel containing amphiphilic microspheres and preparation method thereof 常州药物研究所有限公司 2022-08-19 CN claimed
WO-2022061418-A9 IMPROVEMENTS IN LIQUID CHROMATOGRAPHY SUBSTRATES UNIVERSITY OF SOUTH AUSTRALIA (AU) 2022-04-28 WO claimed
WO-2022061418-A1 IMPROVEMENTS IN LIQUID CHROMATOGRAPHY SUBSTRATES UNIVERSITY OF SOUTH AUSTRALIA (AU) 2022-03-31 WO claimed
CN-114014993-A Preparation method of low-temperature polymerization high-performance polycarboxylate superplasticizer 北京化工大学 2022-02-08 CN claimed
CN-111848848-B Application of silver phosphate as effective photocatalyst for PET-RAFT (polyethylene terephthalate-reversible addition-fragmentation chain transfer) controllable polymerization 清华大学 2021-06-04 CN claimed
WO-2021078082-A1 USE OF ZWITTERION OR ZWITTERIONIC POLYMER AS PH BUFFER MATERIAL 南京师范大学 2021-04-29 WO claimed
CN-111925467-A Application of zwitterion or zwitterion polymer as pH buffering material 南京师范大学 2020-11-13 CN claimed
CN-111848848-A Application of silver phosphate as effective photocatalyst for PET-RAFT (polyethylene terephthalate-reversible addition-fragmentation chain transfer) controllable polymerization 清华大学 2020-10-30 CN claimed
CN-110698576-A Application of zwitterionic polymer as macromolecular pH buffer material 南京师范大学 2020-01-17 CN claimed
US-12624196-B2 Rubber composition, vulcanized object obtained from said rubber composition, and vulcanized molded object obtained from said rubber composition DENKA COMPANY LIMITED (JP) 2026-05-12 US disclosed
US-12599683-B2 Mapping nanoparticles FERRONOVA PTY LTD (AU) 2026-04-14 US disclosed
EP-4719445-A1 PHAGE-EXTRACELLULAR VESICLE CONJUGATE The University Of Sydney (AU) 2026-04-08 EP disclosed
EP-1463765-A4 AQUEOUS DISPERSIONS OF POLYMER PARTICLES UNIV SYDNEY (AU) 2006-05-10 EP disclosed
WO-2006037161-A1 SURFACE POLYMERISATION PROCESS AND POLYMER PRODUCT USING RAFT AGENT THE UNIVERSITY OF SYDNEY (AU) 2006-04-13 WO disclosed
EP-1463765-A1 AQUEOUS DISPERSIONS OF POLYMER PARTICLES University of Sydney (AU) 2004-10-06 EP disclosed
WO-2003055919-A1 AQUEOUS DISPERSIONS OF POLYMER PARTICLES UNIVERSITY OF SYDNEY (AU) 2003-07-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624196-B2 Rubber composition, vulcanized object obtained from said rubber composition, and vulcanized molded object obtained from said rubber composition ALG3, VCL, DNMT1 EPHX1 3116/4885ALDH1A1 2251/4885NPSR1 4660/4885
US-12599683-B2 Mapping nanoparticles FIBP, FAP, ILK EPHX1 3793/4885ALDH1A1 860/4885NPSR1 3032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.