Mearnsetin

Mearnsetin

SCHEMBL3690508

COc1c(O)cc(-c2oc3cc(O)cc(O)c3c(=O)c2O)cc1O

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 6/20 0.81
MEN1 O00255 9/20 0.74
KMT2A Q03164 9/20 0.74
CYP1A2 P05177 8/20 0.74
CYP3A4 P08684 8/20 0.74
CYP1A1 P04798 7/20 0.74
CYP1B1 Q16678 7/20 0.74
KDM4E B2RXH2 7/20 0.74
RECQL P46063 6/20 0.74
HSD17B10 Q99714 6/20 0.74
MAPT P10636 6/20 0.74
CYP2D6 P10635 6/20 0.74
FTO Q9C0B1 5/20 0.74
XDH P47989 5/20 0.74
MAOA P21397 5/20 0.74
IPMK Q8NFU5 5/20 0.74
IP6K2 Q9UHH9 5/20 0.74
POLB P06746 5/20 0.74
CYP2C9 P11712 5/20 0.74
APEX1 P27695 4/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30255771 0.90 ABCB1 (1.00) ABCB1MEN1KMT2ACYP1A2CYP3A4
SCHEMBL4034698 0.90 ABCB1 (1.00) ABCB1MEN1KMT2ACYP1A2CYP3A4
Laricytrin SCHEMBL19213534 0.88 ABCB1 (0.83) ABCB1MEN1KMT2ACYP1A2CYP3A4
Laricytrin SCHEMBL29929477 0.88 ABCB1 (0.83) ABCB1MEN1KMT2ACYP1A2CYP3A4
Syringetin SCHEMBL810981 0.86 ABCB1 (0.85) ABCB1MEN1KMT2ACYP1A2CYP3A4
Syringetin SCHEMBL29929167 0.86 ABCB1 (0.85) ABCB1MEN1KMT2ACYP1A2CYP3A4
SCHEMBL10041306 0.86 POLB (0.77) ABCB1MEN1KMT2ACYP1A2CYP3A4
Myricetin SCHEMBL19302 0.86 MEN1 (1.00) ABCB1MEN1KMT2ACYP1A2CYP3A4
Myricetin SCHEMBL3503992 0.86 MEN1 (1.00) ABCB1MEN1KMT2ACYP1A2CYP3A4
Myricetin SCHEMBL29357150 0.86 MEN1 (1.00) ABCB1MEN1KMT2ACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
WO-2023064318-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC (US) 2023-04-20 WO claimed
CN-115251089-B Application of fleabane extract and method for promoting growth of crops 中国科学院昆明植物研究所 2023-03-10 CN claimed
CN-115251089-A Application of flea grass extract and method for promoting growth of crops 中国科学院昆明植物研究所 2022-11-01 CN claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
US-11786503-B2 Pharmaceutical compositions and methods for countering chemotherapy induced cardiotoxicity AURANSA INC. (US) 2023-10-17 US disclosed
US-11786503-B2 Pharmaceutical compositions and methods for countering chemotherapy induced cardiotoxicity AURANSA INC. (US) 2023-10-17 US disclosed
WO-2023064318-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC (US) 2023-04-20 WO disclosed
CN-115251089-B Application of fleabane extract and method for promoting growth of crops 中国科学院昆明植物研究所 2023-03-10 CN disclosed
CN-115251089-A Application of flea grass extract and method for promoting growth of crops 中国科学院昆明植物研究所 2022-11-01 CN disclosed
US-20220133684-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR COUNTERING CHEMOTHERAPY INDUCED CARDIOTOXICITY AURANSA INC. (US) 2022-05-05 US disclosed
US-11166936-B2 Pharmaceutical compositions and methods for countering chemotherapy induced cardiotoxicity AURANSA INC. (US) 2021-11-09 US disclosed
US-20180222878-A1 COMPOSITION FOR INHIBITING FORMATION OF SNARE COMPLEX, CONTAINING MYRICETIN DERIVATIVES Research & Business Foundation Sungkyunkwan University (KR) 2018-08-09 US disclosed
WO-2017136774-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR COUNTERING CHEMOTHERAPY INDUCED CARDIOTOXICITY STEM CELL THERANOSTICS, INC. (US) 2017-08-10 WO disclosed
US-20170224654-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR COUNTERING CHEMOTHERAPY INDUCED CARDIOTOXICITY STEM CELL THERANOSTICS, INC. (US) 2017-08-10 US disclosed
US-20170224654-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR COUNTERING CHEMOTHERAPY INDUCED CARDIOTOXICITY STEM CELL THERANOSTICS, INC. (US) 2017-08-10 US disclosed
US-8367121-B2 Nutraceutical agent for attenuating the neurodegenerative process associated with Parkinson's disease FLORIDA A & M UNIVERSITY (US) 2013-02-05 US disclosed
US-20100150895-A1 Nutraceutical agent for attenuating the Neurodegenerative process associated with Parkinson's disease NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-06-17 US disclosed
US-20080292607-A1 Nutraceutical agent for attenuating the neurodegenerative process associated with Parkinson's disease MAZZIO ELIZABETH 2008-11-27 US disclosed
US-20070116779-A1 Comprehensive nutraceutical agent for treatment/ prevention of Parkinson's disease MAZZIO ELIZABETH 2007-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11166936-B2 Pharmaceutical compositions and methods for countering chemotherapy induced cardiotoxicity RDX, TNNT2, CHLSN ABCB1 106/4885MEN1 1453/4885KMT2A 1476/4885
US-20170224654-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR COUNTERING CHEMOTHERAPY INDUCED CARDIOTOXICITY RDX, TNNT2, CHLSN ABCB1 106/4885MEN1 1453/4885KMT2A 1476/4885
US-11786503-B2 Pharmaceutical compositions and methods for countering chemotherapy induced cardiotoxicity RDX, TNNT2, CHLSN ABCB1 106/4885MEN1 1453/4885KMT2A 1476/4885
US-20220133684-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR COUNTERING CHEMOTHERAPY INDUCED CARDIOTOXICITY RDX, TNNT2, CHLSN ABCB1 106/4885MEN1 1453/4885KMT2A 1476/4885
US-20180222878-A1 COMPOSITION FOR INHIBITING FORMATION OF SNARE COMPLEX, CONTAINING MYRICETIN DERIVATIVES VAMP7, FLOT1, SNAP29 ABCB1 673/4885MEN1 598/4885KMT2A 2472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.