Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8372617 | 1.00 | ALDH1A1 (0.46) | ALDH1A1APPEPHX2LMNABLM | |
| SCHEMBL6367201 | 1.00 | ALDH1A1 (0.46) | ALDH1A1APPEPHX2LMNABLM | |
| SCHEMBL9446092 | 0.98 | ALDH1A1 (0.45) | ALDH1A1APPEPHX2LMNABLM | |
| SCHEMBL864101 | 0.98 | APP (0.44) | ALDH1A1APPEPHX2LMNABLM | |
| SCHEMBL3177040 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL5063686 | 0.88 | APP (0.44) | ALDH1A1APPEPHX2LMNABLM | |
| SCHEMBL10324781 | 0.88 | APP (0.44) | ALDH1A1APPEPHX2LMNABLM | |
| SCHEMBL22800820 | 0.86 | TSHR (0.40) | ALDH1A1EPHX2LMNACYP2C19KDM4E | |
| SCHEMBL22800817 | 0.86 | TSHR (0.40) | ALDH1A1EPHX2LMNACYP2C19KDM4E | |
| SCHEMBL22800823 | 0.86 | TSHR (0.40) | ALDH1A1EPHX2LMNACYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331547-A1 | COMPOSITIONS WITH PERMEATION ENHANCERS FOR DRUG DELIVERY | Children's Medical Center Corporation (US) | 2018-06-13 | — | — | EP | disclosed |
| WO-2017024282-A1 | COMPOSITIONS WITH PERMEATION ENHANCERS FOR DRUG DELIVERY | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2017-02-09 | — | — | WO | disclosed |
| EP-2166837-A1 | DRUG COMBINATION FOR THE TREATMENT OF SKIN DISORDERS | Prugen, Inc. (US) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008156798-A1 | DRUG COMBINATION FOR THE TREATMENT OF SKIN DISORDERS | PRUGEN, INC. (US) | 2008-12-24 | — | — | WO | disclosed |
| EP-0914076-A1 | RINSE-OFF HAIR CARE COMPOSITIONS USING GRAFTED COPOLYMERS | THE PROCTER & GAMBLE COMPANY (US) | 1999-05-12 | — | — | EP | disclosed |
| EP-0914077-A1 | LOW RESIDUE HAIR CARE COMPOSITIONS USING GRAFTED COPOLYMERS | THE PROCTER & GAMBLE COMPANY (US) | 1999-05-12 | — | — | EP | disclosed |
| EP-0896518-A2 | LOW RESIDUE HAIR CARE COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1999-02-17 | — | — | EP | disclosed |
| WO-1998012920-A9 | METHODS FOR PREPARING SPONTANEOUSLY WATER DISPERSIBLE CARRIERS FOR PESTICIDES AND THEIR USE | — | 1998-09-03 | — | — | WO | disclosed |
| WO-1998012921-A1 | SPONTANEOUSLY WATER DISPERSIBLE CARRIER FOR PESTICIDES | RHODIA INC. (US) | 1998-04-02 | — | — | WO | disclosed |
| WO-1997034571-A1 | RINSE-OFF HAIR CARE COMPOSITIONS USING GRAFTED COPOLYMERS | THE PROCTER & GAMBLE COMPANY (US) | 1997-09-25 | — | — | WO | disclosed |
| WO-1997034572-A1 | LOW RESIDUE HAIR CARE COMPOSITIONS USING GRAFTED COPOLYMERS | THE PROCTER & GAMBLE COMPANY (US) | 1997-09-25 | — | — | WO | disclosed |
| WO-1997034574-A2 | LOW RESIDUE HAIR CARE COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1997-09-25 | — | — | WO | disclosed |
| EP-0625040-A1 | SHAMPOO PREMIX COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1994-11-23 | — | — | EP | disclosed |
| WO-1993015711-A1 | SHAMPOO PREMIX COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1993-08-19 | — | — | WO | disclosed |
| WO-1992010162-A1 | SHAMPOO COMPOSITIONS WITH SILICONE AND CATIONIC ORGANIC POLYMERIC CONDITIONING AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1992-06-25 | — | — | WO | disclosed |
| EP-0412707-A1 | Hair conditioning and styling compositions | THE PROCTER & GAMBLE COMPANY (US) | 1991-02-13 | — | — | EP | disclosed |
| EP-0412704-A2 | Hair conditioning and styling compositions | THE PROCTER & GAMBLE COMPANY (US) | 1991-02-13 | — | — | EP | disclosed |