Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 2/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.31 |
| ▸ | CDK9 | P50750 | 2/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3700587 | 0.93 | PLA2G10 (0.38) | PLA2G10PLA2G5KDM4EALDH1A1CHRM3 | |
| SCHEMBL30069168 | 0.88 | PLA2G10 (0.35) | PLA2G10PLA2G5KDM4EALDH1A1CHRM3 | |
| SCHEMBL9925280 | 0.87 | PLA2G10 (0.34) | PLA2G10PLA2G5KDM4EALDH1A1CHRM3 | |
| SCHEMBL29673006 | 0.84 | CHRM5 (0.38) | SIGMAR1CHRM3DDB1CRBNCHRM5 | |
| SCHEMBL1241407 | 0.83 | CHRM5 (0.39) | SIGMAR1CHRM3DDB1CRBNCHRM5 | |
| SCHEMBL18022129 | 0.83 | PLA2G10 (0.34) | PLA2G10PLA2G5CHRM3CHRM2CHRM4 | |
| SCHEMBL4771744 | 0.81 | SIGMAR1 (0.47) | PLA2G10PLA2G5SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL12231841 | 0.81 | CHRM5 (0.34) | SIGMAR1CHRM3CHRM5 | |
| SCHEMBL1149470 | 0.80 | SIGMAR1 (0.49) | PLA2G10PLA2G5SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL583320 | 0.80 | SIGMAR1 (0.49) | PLA2G10PLA2G5SIGMAR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234450-A1 | Molecular targeting agents | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234450-A1 | Molecular targeting agents | CD2BP2, CD47, ANXA6 | PLA2G10 4240/4885PLA2G5 3725/4885SIGMAR1 2425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.