Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29673006 | 0.98 | CHRM5 (0.38) | CHRM5CHRM3SIGMAR1EGFRMEN1 | |
| SCHEMBL14522328 | 0.93 | CHRM5 (0.35) | CHRM5CHRM3SIGMAR1EGFR | |
| SCHEMBL12038457 | 0.93 | CHRM5 (0.35) | CHRM5CHRM3SIGMAR1EGFR | |
| SCHEMBL12231841 | 0.91 | CHRM5 (0.34) | CHRM5CHRM3SIGMAR1EGFR | |
| SCHEMBL20976685 | 0.84 | MEN1 (0.35) | MEN1KMT2ADDB1CRBN | |
| SCHEMBL3690735 | 0.83 | PLA2G10 (0.37) | CHRM5CHRM3SIGMAR1DDB1CRBN | |
| SCHEMBL1241402 | 0.83 | GAA (0.41) | CHRM5CHRM3MEN1KMT2A | |
| SCHEMBL6666931 | 0.83 | SLC6A9 (0.33) | CHRM5CHRM3MGLL | |
| SCHEMBL560792 | 0.81 | HSD17B10 (0.39) | MEN1KMT2AMGLL | |
| SCHEMBL15518427 | 0.81 | HSD17B10 (0.39) | MEN1KMT2AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8679773-B2 | Kits pertaining to analyte determination | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. (SG) | 2014-03-25 | — | — | US | disclosed |
| EP-2251334-B1 | Labeling reagents and labeled analytes | DH TECHNOLOGIES DEV PTE LTD (SG) | 2013-08-14 | — | — | EP | disclosed |
| US-8273706-B2 | Isobarically labeled analytes and fragment ions derived therefrom | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. (SG) | 2012-09-25 | — | — | US | disclosed |
| US-20110217720-A1 | Compositions and Kits Pertaining to Analyte Determination | PAPPIN DARRYL J C | 2011-09-08 | — | — | US | disclosed |
| EP-1588145-B1 | METHODS, MIXTURES, KITS AND COMPOSITIONS PERTAINING TO ANALYTE DETERMINATION | LIFE TECHNOLOGIES CORP (US) | 2011-07-06 | — | — | EP | disclosed |
| US-20110143445-A1 | Analysis of Amino Acids And Amine-Containing Compounds Using Tagging Reagents and LC-MS Workflow | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. (SG) | 2011-06-16 | — | — | US | disclosed |
| US-7947513-B2 | Sets and compositions pertaining to analyte determination | DH Technologies Ptd. Ltd. (SG) | 2011-05-24 | — | — | US | disclosed |
| US-7910059-B2 | For the determination of an analyte or analytes such as proteins, peptides, nucleic acids, carbohydrates, lipids, steroids and small molecules by mass analysis | DH TECHNOLOGIES PTE. LTD. (SG) | 2011-03-22 | — | — | US | disclosed |
| US-20110045516-A1 | Kits Pertaining to Analyte Determination | APPLERA CORPORATION (US) | 2011-02-24 | — | — | US | disclosed |
| EP-2251334-A1 | Labeling reagents and labeled analytes | Life Technologies Corporation (US) | 2010-11-17 | — | — | EP | disclosed |
| US-7195751-B2 | Compositions and kits pertaining to analyte determination | APPLERA CORPORATION (US) | 2007-03-27 | — | — | US | disclosed |
| EP-1701945-A1 | LABELING REAGENTS, LABELED ANALYTES, INCLUDING MIXTURES THEREOF, AND FRAGMENT IONS DERIVED THEREFROM AND METHODS FOR THE ANALYSIS THEREOF | Applera Corporation (US) | 2006-09-20 | — | — | EP | disclosed |
| US-20060105416-A1 | Methods, compositions and kits pertaining to analyte determination | APPLERA CORPORATION (US) | 2006-05-18 | — | — | US | disclosed |
| EP-1588145-A2 | METHODS, MIXTURES, KITS AND COMPOSITIONS PERTAINING TO ANALYTE DETERMINATION | Applera Corporation (US) | 2005-10-26 | — | — | EP | disclosed |
| WO-2005068446-A1 | LABELING REAGENTS, LABELED ANALYTES, INCLUDING MIXTURES THEREOF, AND FRAGMENT IONS DERIVED THEREFROM AND METHODS FOR THE ANALYSIS THEREOF | APPLERA CORPORATION (US) | 2005-07-28 | — | — | WO | disclosed |
| US-20050148087-A1 | Isobarically labeled analytes and fragment ions derived therefrom | APPLERA CORPORATION | 2005-07-07 | — | — | US | disclosed |
| US-20040219686-A1 | Methods and mixtures pertaining to analyte determination | APPLIED BIOSYSTEMS, LLC | 2004-11-04 | — | — | US | disclosed |
| US-20040220412-A1 | Compositions and kits pertaining to analyte determination | APPLE CORPORATION | 2004-11-04 | — | — | US | disclosed |
| US-20040219685-A1 | Methods and mixtures pertaining to analyte determination using electrophilic labeling reagents | APPLERA CORPORATION | 2004-11-04 | — | — | US | disclosed |
| WO-2004070352-A2 | METHODS, MIXTURES, KITS AND COMPOSITIONS PERTAINING TO ANALYTE DETERMINATION | APPLERA CORPORATION (US) | 2004-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060105416-A1 | Methods, compositions and kits pertaining to analyte determination | SRMS, SHBG, KLK3 | CHRM5 1872/4885CHRM3 1881/4885SIGMAR1 4337/4885 |
| US-20050148087-A1 | Isobarically labeled analytes and fragment ions derived therefrom | KLK3, SRMS, PTMS | CHRM5 4346/4885CHRM3 3442/4885SIGMAR1 4000/4885 |
| US-20040220412-A1 | Compositions and kits pertaining to analyte determination | KLK3, SRMS, SHBG | CHRM5 2165/4885CHRM3 2094/4885SIGMAR1 4443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.