Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.36 |
| ▸ | FPR3 | P25089 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5793665 | 0.74 | CYP2D6 (0.39) | CYP1A2CYP2D6POLB | |
| SCHEMBL2488210 | 0.70 | TYR (0.41) | — | |
| SCHEMBL9640284 | 0.70 | CHRM2 (0.46) | — | |
| SCHEMBL1851579 | 0.68 | KMT2A (0.39) | POLBSLC6A4SLC6A3 | |
| SCHEMBL3690761 | 0.68 | CYP2D6 (1.00) | CYP1A2CYP2D6TSHRPOLB | |
| SCHEMBL5790059 | 0.68 | ALDH1A1 (0.40) | TSHRPOLB | |
| SCHEMBL467252 | 0.67 | CYP1A2 (0.45) | CYP1A2CYP2D6TSHR | |
| SCHEMBL6017223 | 0.66 | CYP2D6 (0.46) | CYP1A2CYP2D6TSHRPOLBSLC6A4 | |
| Hydrochloric Acid SCHEMBL9373976 | 0.65 | CNR2 (0.37) | — | |
| SCHEMBL3485175 | 0.64 | DRD3 (0.42) | CYP1A2CYP2D6TSHRSLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2148673-A1 | CINNAMIDE COMPOUNDS FOR DEMENTIA | Eisai R&D Management Co., Ltd. (JP) | 2010-02-03 | — | — | EP | disclosed |
| WO-2008139984-A1 | CINNAMIDE COMPOUNDS FOR DEMENTIA | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2008-11-20 | — | — | WO | disclosed |