Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8860177 | 0.85 | SLC6A9 (0.39) | CYP2D6LMNACYP2C9HSD17B10SLC6A9 | |
| SCHEMBL9640284 | 0.78 | CHRM2 (0.46) | CHRM2CHRM1CHRM3CHRM4MEN1 | |
| SCHEMBL2488210 | 0.77 | TYR (0.41) | KDM4E | |
| SCHEMBL3485175 | 0.75 | DRD3 (0.42) | CYP2D6LMNASLC6A9CHRM2CHRM1 | |
| SCHEMBL5790059 | 0.75 | ALDH1A1 (0.40) | LMNASMN1; SMN2KDM4EPOLBKMT2A | |
| SCHEMBL3690763 | 0.74 | CYP1A2 (0.51) | CYP2D6CYP1A2POLB | |
| Hydrochloric Acid SCHEMBL4152474 | 0.74 | DRD3 (0.41) | CYP2D6LMNACHRM2CHRM1CHRM3 | |
| SCHEMBL1851579 | 0.68 | KMT2A (0.39) | KDM4EMEN1POLBKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL6678403 | 0.68 | MEN1 (0.50) | CYP2D6LMNACHRM2CHRM1SMN1; SMN2 | |
| SCHEMBL5793663 | 0.68 | LMNA (0.76) | CYP2D6LMNACYP2C9HSD17B10CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006010246-A1 | THE ISOLATION AND CHARACTERIZATION OF A GENE ENCODING A LITTORINE MUTASE/HYDROXYLASE, TRANSGENIC PLANTS AND USES THEREOF FOR ALERTING ALKALOID BIOSYNTHESIS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2006-02-02 | — | — | WO | disclosed |