SCHEMBL3690807

SCHEMBL3690807

O=C=NCCCCCCCCCCCCN=C=O.O=C=NCCCCCCSCCCCCCN=C=O

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 4/20 0.40
NAAA Q02083 1/20 0.30
MIF P14174 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL331429 1.00 TRPA1 (0.40) TRPA1NAAAMIF
SCHEMBL28170081 0.95 TRPA1 (0.38) TRPA1
SCHEMBL5082862 0.95 TRPA1 (0.35) TRPA1NAAAMIF
SCHEMBL28154696 0.93 TRPA1 (0.35) TRPA1
SCHEMBL331679 0.90 TRPA1 (0.36) TRPA1
SCHEMBL11725725 0.89 NAAA (0.47) TRPA1NAAA
SCHEMBL29913930 0.89 TRPA1 (0.36) TRPA1
SCHEMBL11726640 0.87 TRPA1 (0.36) TRPA1NAAA
SCHEMBL21145631 0.86 TRPA1 (0.32) TRPA1
SCHEMBL484024 0.85 TRPA1 (0.40) TRPA1NAAAMIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3448904-B1 PROCESS FOR PRODUCING AN IMPROVED FLEXIBLE FOAM USING POLYMER POLYOLS PRODUCED VIA DMC CATALYZED POLYOLS COVESTRO LLC (US) 2024-01-31 EP disclosed
US-11312811-B2 Flexible foam using polymer polyols produced via DMC catalyzed polyols COVESTRO LLC (US) 2022-04-26 US disclosed
EP-2710047-B1 A FOAM COMPOSITION AND ITS USES THEREOF MAS INNOVATION PRIVATE LTD (LK) 2019-09-11 EP disclosed
US-20170306076-A1 FLEXIBLE FOAM USING POLYMER POLYOLS PRODUCED VIA DMC CATALYZED POLYOLS COVESTRO LLC 2017-10-26 US disclosed
US-9382399-B2 Foam composition and its uses thereof MAS INNOVATION (PRIVATE) LIMITED (LK) 2016-07-05 US disclosed
EP-2707217-B1 METHOD OF MANUFACTURING A FABRIC-LAMINATED FOAM ARTICLE MAS INNOVATION PRIVATE LTD (LK) 2015-07-29 EP disclosed
US-20140120337-A1 Method of Manufacturing a Fabric-Laminated Foam Article MAS RESEARCH AND INNOVATION (PVT) LTD. (LK) 2014-05-01 US disclosed
US-20140079940-A1 Foam Composition and its Uses Thereof MAS RESEARCH AND INNOVATION (PVT) LTD. (LK) 2014-03-20 US disclosed
CN-103534288-A A foam composition and its uses thereof MAS RES AND INNOVATION PVT LTD 2014-01-22 CN disclosed
US-7759423-B2 Polymer polyols with ultra-high solids contents BAYER MATERIALSCIENCE LLC (US) 2010-07-20 US disclosed
US-4312973-A HYDROLYTIC STABILITY UNION CARBIDE CORPORATION (US) 1982-01-26 US disclosed
US-4282331-A Polyurethane foam prepared from a copolymer/polyol composition UNION CARBIDE CORPORATION (US) 1981-08-04 US disclosed
US-4242249-A ADDITION POLYMER WITH POLYOXYPROPYLENE GRAFTS UNION CARBIDE CORPORATION (US) 1980-12-30 US disclosed
US-4208314-A LOW DENSITY POLYURETHANE FOAMS FROM POLYOLS WITH ADDITION POLYMER PARTICLES CONTAINED THEREIN UNION CARBIDE CORPORATION (US) 1980-06-17 US disclosed
US-4172825-A Polymer/polyols and process for production thereof UNION CARBIDE CORPORATION (US) 1979-10-30 US disclosed
US-4162353-A HALOPHOSPHATES OR POLYMERS THEREOF UNION CARBIDE CORPORATION (US) 1979-07-24 US disclosed
US-4148840-A Polymer/polyol compositions made from preformed polymer/polyols, processes for making same and processes for making polyurethane products therefrom UNION CARBIDE CORPORATION (US) 1979-04-10 US disclosed
US-4143002-A CHALK-RESISTANT, MEDIUM TO DARK COLORED POLYURETHANES, POLYMER/POLYOL AND POLYISOCYANATE COMPOSITIONS FOR USE IN PRODUCING SAME AND METHODS FOR MAKING SAID POLYURETHANES UNION CARBIDE CORPORATION (US) 1979-03-06 US disclosed
US-4119586-A Polymer/polyol compositions, processes for making same and processes for making polyurethane products therefrom UNION CARBIDE CORPORATION (US) 1978-10-10 US disclosed
US-4097559-A TRIS(2-CHLORO-ETHYL)PHOSPHATE, TRIETHYL PHOSPHATE UNION CARBIDE CORPORATION (US) 1978-06-27 US disclosed