Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3692633 | 0.79 | VHL (0.57) | VHLOPRM1OPRD1OPRK1XIAP | |
| SCHEMBL3690891 | 0.77 | VHL (0.52) | VHLOPRM1OPRD1OPRK1XIAP | |
| SCHEMBL2071996 | 0.76 | VHL (0.54) | VHLOPRM1OPRD1OPRK1XIAP | |
| SCHEMBL2074852 | 0.76 | VHL (0.56) | VHLOPRM1OPRD1OPRK1XIAP | |
| SCHEMBL2075246 | 0.75 | VHL (0.51) | VHLOPRM1OPRD1OPRK1XIAP | |
| SCHEMBL2073451 | 0.75 | VHL (0.51) | VHLOPRM1OPRD1OPRK1XIAP | |
| SCHEMBL2072287 | 0.73 | VHL (0.49) | VHLOPRM1OPRD1OPRK1XIAP | |
| SCHEMBL2075127 | 0.73 | VHL (0.49) | VHLOPRM1OPRD1OPRK1XIAP | |
| SCHEMBL2075366 | 0.73 | VHL (0.54) | VHLOPRM1OPRD1OPRK1XIAP | |
| SCHEMBL2072259 | 0.72 | VHL (0.48) | VHLOPRM1OPRD1OPRK1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306042-A1 | Novel Compounds 010 | ASTRAZENECA AB (SE) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306042-A1 | Novel Compounds 010 | MRGPRX2, F12, TBXA2R | VHL 4069/4885OPRM1 332/4885OPRD1 240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.