Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RBP4 | P02753 | 5/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900103 | 1.00 | GAA (0.44) | GAATDP1RBP4HTR2CHTR2B | |
| SCHEMBL12462449 | 0.83 | RBP4 (0.47) | GAATDP1RBP4HTR2CHTR2B | |
| SCHEMBL187797 | 0.83 | RBP4 (0.47) | GAATDP1RBP4HTR2CHTR2B | |
| SCHEMBL21451909 | 0.70 | GAA (0.49) | GAATDP1RBP4HTR2CHTR2B | |
| SCHEMBL9282768 | 0.69 | PSEN1 (0.54) | GAATDP1RBP4HTR2CPSEN1 | |
| SCHEMBL908685 | 0.69 | NTRK1 (0.42) | RBP4 | |
| SCHEMBL909802 | 0.68 | TP53 (0.41) | GAATDP1RBP4HTR2CHTR2B | |
| SCHEMBL25378056 | 0.67 | HTR2C (0.49) | GAATDP1RBP4HTR2CHTR2B | |
| SCHEMBL16212148 | 0.67 | HTR2C (0.49) | GAATDP1RBP4HTR2CHTR2B | |
| SCHEMBL31227327 | 0.67 | HTR2C (0.49) | GAATDP1RBP4HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010098496-A1 | PROCESS FOR PRODUCING TETRAHYDROTRIAZOLOPYRIDINE DERIVATIVE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-09-02 | — | — | WO | disclosed |