Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.34 |
| ▸ | HTR1B | P28222 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3274613 | 0.79 | MAPT (0.62) | CYP2C9MAPTCYP2C19CYP1A2TDP1 | |
| SCHEMBL1933357 | 0.76 | TLR8 (0.38) | MAPTGAATDP1L3MBTL1HTR1B | |
| SCHEMBL30456416 | 0.76 | TLR8 (0.38) | MAPTGAATDP1L3MBTL1HTR1B | |
| SCHEMBL15076880 | 0.75 | SLC2A1 (0.34) | MAPTCYP2C19CYP1A2GAATDP1 | |
| SCHEMBL16241795 | 0.72 | MAPT (0.54) | CYP2C9MAPTCYP2C19CYP1A2TDP1 | |
| SCHEMBL19222664 | 0.71 | MAPT (0.53) | CYP2C9MAPTCYP2C19CYP1A2GAA | |
| SCHEMBL30719117 | 0.70 | MAPT (0.55) | CYP2C9MAPTCYP2C19CYP1A2TDP1 | |
| SCHEMBL5387322 | 0.70 | HTR1B (0.40) | CYP2C9CYP2C19CYP1A2GAATDP1 | |
| SCHEMBL14232481 | 0.69 | MAPT (0.54) | CYP2C9MAPTCYP2C19CYP1A2L3MBTL1 | |
| SCHEMBL19328692 | 0.69 | CA1 (0.38) | MAPTCYP3A4IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593439-A2 | PROCESS FOR PREPARING ANTIVIRAL COMPOUNDS | Abbvie Inc. (US) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012009699-A2 | PROCESS FOR PREPARING ANTIVIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2012-01-19 | — | — | WO | disclosed |