SCHEMBL15076880

SCHEMBL15076880

CCCCPCc1ccc2ccccc2c1-c1c(PCCCC)ccc2ccccc12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 2/20 0.34
GAA P10253 5/20 0.32
RAB9A P51151 5/20 0.32
MEN1 O00255 4/20 0.32
KMT2A Q03164 4/20 0.32
KDM4E B2RXH2 4/20 0.32
NPC1 O15118 4/20 0.32
ALDH1A1 P00352 4/20 0.32
HTT P42858 4/20 0.32
SMN1; SMN2 Q16637 4/20 0.32
TDP1 Q9NUW8 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
GLA P06280 1/20 0.32
RCE1 Q9Y256 1/20 0.32
KCNH2 Q12809 1/20 0.32
NPSR1 Q6W5P4 2/20 0.32
HPGD P15428 2/20 0.32
MAPK1 P28482 2/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30456416 0.79 TLR8 (0.38) GAARAB9AMEN1KMT2AKDM4E
SCHEMBL1933357 0.79 TLR8 (0.38) GAARAB9AMEN1KMT2AKDM4E
SCHEMBL369244 0.75 CYP2C9 (0.43) GAATDP1L3MBTL1KCNH2CYP1A2
SCHEMBL5387322 0.73 HTR1B (0.40) GAARAB9AMEN1KMT2AKDM4E
SCHEMBL15888330 0.71 KCNH2 (0.31) TDP1KCNH2
SCHEMBL8158005 0.71 TLR8 (0.40) RAB9AMEN1KMT2AKDM4ENPC1
SCHEMBL16317965 0.70 ATM (0.39) SLC2A1ALDH1A1TDP1MAPTTSHR
SCHEMBL14404520 0.70 LIPG (0.38) HTTKCNH2CYP1A2CYP2D6CYP2C19
SCHEMBL16671703 0.70 TLR8 (0.45) GAARAB9AMEN1KMT2AKDM4E
SCHEMBL3674710 0.68 LIPG (0.47) GAARAB9AMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9382190-B2 Continuous process for the carbonylation of ethylene LUCITE INTERNATIONAL UK LIMITED (GB) 2016-07-05 US disclosed
US-20150099896-A1 CONTINUOUS PROCESS FOR THE CARBONYLATION OF ETHYLENE LUCITE INTERNATIONAL UK LIMITED (GB) 2015-04-09 US disclosed
US-8785678-B2 Continuous process for the carbonylation of ethylene LUCITE INTERNATIONAL UK LIMITED (GB) 2014-07-22 US disclosed
WO-2013093472-A1 A CONTINUOUS PROCESS FOR THE CARBONYLATION OF ETHYLENE LUCITE INTERNATIONAL UK LIMITED (GB) 2013-06-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150099896-A1 CONTINUOUS PROCESS FOR THE CARBONYLATION OF ETHYLENE SCD, ELOVL6, ALK SLC2A1 2059/4885GAA 3636/4885RAB9A 3338/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.