Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3686635 | 1.00 | SLC6A2 (0.33) | SLC6A2SLC6A4SSTR4KDM4EMAPT | |
| SCHEMBL22009149 | 0.85 | SSTR4 (0.33) | SLC6A2SLC6A4SSTR4 | |
| SCHEMBL27602139 | 0.80 | SLC6A2 (0.31) | SLC6A2SLC6A4SSTR4 | |
| SCHEMBL9235040 | 0.78 | DRD2 (0.31) | SSTR4 | |
| SCHEMBL19387694 | 0.78 | DRD2 (0.31) | SSTR4 | |
| SCHEMBL27602134 | 0.77 | SLC6A2 (0.33) | SLC6A2SLC6A4 | |
| SCHEMBL28500314 | 0.77 | GLO1 (0.33) | SLC6A2SLC6A4SSTR4MAPT | |
| SCHEMBL28199175 | 0.76 | SSTR4 (0.31) | SSTR4 | |
| SCHEMBL5963180 | 0.72 | SLC6A2 (0.34) | SLC6A2SLC6A4SSTR4KDM4EMAPT | |
| SCHEMBL4238090 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814515-B2 | OPHTHALMIC COMPOSITIONS COMPRISING POLYETHER SUBSTITUTED POLYMERS | JOHNSON AND JOHNSON VISION CARE INC (US) | 2020-04-01 | — | — | EP | claimed |
| EP-1814515-B1 | OPHTHALMIC COMPOSITIONS COMPRISING POLYETHER SUBSTITUTED POLYMERS | JOHNSON & JOHNSON VISION CARE (US) | 2010-03-17 | — | — | EP | claimed |
| EP-2112182-A1 | Polymerizable composition, light-shielding color filter, black curable composition, light-shielding color filter for solid-state image pickup device and method of producing the same, and solid-state image pickup device | FUJIFILM Corporation (JP) | 2009-10-28 | — | — | EP | disclosed |