Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25645644 | 0.87 | TSHR (0.63) | TSHRKMT2AMEN1NPC1SMN1; SMN2 | |
| Potassium Ion SCHEMBL8104536 | 0.84 | TSHR (0.59) | TSHRKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL4686902 | 0.84 | TSHR (0.55) | TSHRKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL28458528 | 0.84 | TSHR (0.59) | TSHRKMT2AMEN1NPC1SMN1; SMN2 | |
| Lithium Ion SCHEMBL8120162 | 0.84 | TSHR (0.59) | TSHRKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL10607548 | 0.82 | TSHR (0.68) | TSHRKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL9615248 | 0.81 | TSHR (0.72) | TSHRKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL11473827 | 0.81 | TSHR (0.72) | TSHRKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL755941 | 0.80 | TSHR (0.59) | TSHRKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL9281988 | 0.80 | TSHR (0.64) | TSHRKMT2AMEN1NPC1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642073-B2 | Using mixture comprising modified alcohol dehydrogenase, ammonia, nicotinamide and 2-ketoacid to generate preferential amino acids | CODEXIS, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-20080076162-A1 | Using mixture comprising modified alcohol dehydrogenase, ammonia, nicotinamide and 2-ketoacid to generate preferential amino acids | BIOCATALYTICS, INC. | 2008-03-27 | — | — | US | disclosed |
| US-7202070-B2 | Generating phenylalanine and leucine using mutant enzymatic polypeptide; generate mutant enzyme, aminate ketoacid, recover amino acids | BIOCATALYTICS, INC. (US) | 2007-04-10 | — | — | US | disclosed |
| EP-1369410-A1 | Process for the stereoselective reduction of derivatives of 4-aryl-4-oxobutyric acid | BAYER AG (DE) | 2003-12-10 | — | — | EP | disclosed |
| US-20020061564-A1 | Generating phenylalanine and leucine using mutant enzymatic polypeptide; generate mutant enzyme, aminate ketoacid, recover amino acids | CODEXIS, INC. | 2002-05-23 | — | — | US | disclosed |
| WO-2002036742-A2 | METHOD FOR CHEMICAL TRANSFORMATION USING A MUTATED ENZYME | BIOCATALYTICS, INC. (US) | 2002-05-10 | — | — | WO | disclosed |
| US-6126855-A | Reaction products of lyotropic liquid crystal salt complexes | ELLIOTT STANLEY B (US) | 2000-10-03 | — | — | US | disclosed |
| US-5833877-A | DIAGMAGNETIC COMPLEX; SUPERCONDUCTORS | ELLIOTT STANLEY B (US) | 1998-11-10 | — | — | US | disclosed |
| US-5595683-A | COMPLEX OF METAL SALT OF BENZOYLPROPIONIC ACID, LATTICE MODIFIER, CYCLIZATION, HUMIDITY SENSORS | ELLIOTT STANLEY B (US) | 1997-01-21 | — | — | US | disclosed |
| US-5443753-A | Reaction products of lyotropic liquid crystal salt complexes | ELLIOTT STANLEY B (US) | 1995-08-22 | — | — | US | disclosed |
| US-5354499-A | Reaction products of lyotropic liquid crystal salt complexes | ELLIOTT STANLEY B (US) | 1994-10-11 | — | — | US | disclosed |
| US-5354496-A | Lyotropic liquid crystal salt/inorganic compound complexation products | ELLIOTT STANLEY B (US) | 1994-10-11 | — | — | US | disclosed |
| US-5082588-A | Hygrometers | ELLIOTT STANLEY B (US) | 1992-01-21 | — | — | US | disclosed |
| US-4975249-A | Optical and capacitance type, phase transition, humidity-responsive devices | ELLIOTT STANLEY B (US) | 1990-12-04 | — | — | US | disclosed |