Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | MMP2 | P08253 | 2/20 | 0.58 |
| ▸ | MMP12 | P39900 | 2/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
| ▸ | MMP14 | P50281 | 1/20 | 0.58 |
| ▸ | MMP15 | P51511 | 1/20 | 0.58 |
| ▸ | MMP16 | P51512 | 1/20 | 0.58 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13405656 | 0.88 | TSHR (0.73) | TSHRKMT2ANPC1MEN1L3MBTL1 | |
| SCHEMBL3693703 | 0.87 | TSHR (0.78) | TSHRKMT2ANPC1MEN1MMP2 | |
| SCHEMBL8114344 | 0.87 | MMP2 (0.73) | TSHRKMT2ANPC1MEN1MMP2 | |
| SCHEMBL1629814 | 0.86 | MMP2 (0.57) | TSHRKMT2ANPC1MEN1MMP2 | |
| SCHEMBL8120164 | 0.85 | MMP2 (0.71) | TSHRKMT2ANPC1MEN1MMP2 | |
| Water SCHEMBL28896308 | 0.84 | MMP2 (0.56) | TSHRKMT2ANPC1MEN1MMP2 | |
| Potassium Ion SCHEMBL8104538 | 0.82 | MMP2 (0.55) | TSHRKMT2ANPC1MEN1MMP2 | |
| Lithium Ion SCHEMBL8120162 | 0.82 | TSHR (0.59) | TSHRKMT2ANPC1MEN1L3MBTL1 | |
| SCHEMBL28458528 | 0.82 | TSHR (0.59) | TSHRKMT2ANPC1MEN1L3MBTL1 | |
| Potassium Ion SCHEMBL8104536 | 0.82 | TSHR (0.59) | TSHRKMT2ANPC1MEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107557-A1 | COMPOUNDS AND COMPOSITIONS THAT INHIBIT PIKFYVE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |