Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL8120162 | 0.97 | TSHR (0.59) | TSHRKMT2AMEN1NPC1L3MBTL1 | |
| SCHEMBL28458528 | 0.97 | TSHR (0.59) | TSHRKMT2AMEN1NPC1L3MBTL1 | |
| SCHEMBL3693703 | 0.84 | TSHR (0.78) | TSHRKMT2AMEN1NPC1L3MBTL1 | |
| SCHEMBL25645644 | 0.82 | TSHR (0.63) | TSHRKMT2AMEN1NPC1L3MBTL1 | |
| Potassium Ion SCHEMBL8104538 | 0.76 | MMP2 (0.55) | TSHRKMT2AMEN1NPC1L3MBTL1 | |
| SCHEMBL755941 | 0.76 | TSHR (0.59) | TSHRKMT2AMEN1NPC1L3MBTL1 | |
| SCHEMBL8114355 | 0.75 | L3MBTL1 (0.60) | TSHRKMT2AMEN1NPC1L3MBTL1 | |
| SCHEMBL9225409 | 0.74 | TSHR (0.57) | TSHRKMT2AMEN1NPC1L3MBTL1 | |
| SCHEMBL11768086 | 0.74 | TSHR (0.57) | TSHRKMT2AMEN1NPC1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL29091991 | 0.74 | TSHR (0.57) | TSHRKMT2AMEN1NPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6126855-A | Reaction products of lyotropic liquid crystal salt complexes | ELLIOTT STANLEY B (US) | 2000-10-03 | — | — | US | disclosed |
| US-5833877-A | DIAGMAGNETIC COMPLEX; SUPERCONDUCTORS | ELLIOTT STANLEY B (US) | 1998-11-10 | — | — | US | disclosed |
| US-5595683-A | COMPLEX OF METAL SALT OF BENZOYLPROPIONIC ACID, LATTICE MODIFIER, CYCLIZATION, HUMIDITY SENSORS | ELLIOTT STANLEY B (US) | 1997-01-21 | — | — | US | disclosed |
| US-5443753-A | Reaction products of lyotropic liquid crystal salt complexes | ELLIOTT STANLEY B (US) | 1995-08-22 | — | — | US | disclosed |
| US-5354499-A | Reaction products of lyotropic liquid crystal salt complexes | ELLIOTT STANLEY B (US) | 1994-10-11 | — | — | US | disclosed |
| US-5354496-A | Lyotropic liquid crystal salt/inorganic compound complexation products | ELLIOTT STANLEY B (US) | 1994-10-11 | — | — | US | disclosed |