Dimethylamine

Dimethylamine

SCHEMBL3693873

CNC.Cc1cccc(C)c1N=Nc1ccc(N=Nc2ccc(N=Nc3c(C)cccc3C)cc2)cc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.52
▸ KMT2A Q03164 4/20 0.52
▸ HSP90AA1 P07900 1/20 0.52
▸ ATM Q13315 1/20 0.52
▸ NPC1 O15118 3/20 0.41
▸ RAB9A P51151 2/20 0.41
▸ ALDH1A1 P00352 3/20 0.39
▸ GRIN2D O15399 2/20 0.37
▸ GRIN3B O60391 2/20 0.37
▸ GRIN1 Q05586 2/20 0.37
▸ GRIN2A Q12879 2/20 0.37
▸ GRIN2B Q13224 2/20 0.37
▸ GRIN2C Q14957 2/20 0.37
▸ GRIN3A Q8TCU5 2/20 0.37
▸ SIGMAR1 Q99720 2/20 0.37
▸ MAPT P10636 5/20 0.36
▸ TDP1 Q9NUW8 3/20 0.36
▸ NSD2 O96028 1/20 0.36
▸ CASP3 P42574 1/20 0.36
▸ SENP8 Q96LD8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL11589331 0.89 MEN1 (0.43) MEN1KMT2AHSP90AA1ATMNPC1
SCHEMBL16594278 0.84 ALDH1A1 (0.57) MEN1KMT2AHSP90AA1ATMNPC1
SCHEMBL16594280 0.84 ALDH1A1 (0.57) MEN1KMT2AHSP90AA1ATMNPC1
SCHEMBL11151430 0.83 MEN1 (0.64) MEN1KMT2AHSP90AA1ATMNPC1
SCHEMBL11151415 0.83 MEN1 (0.64) MEN1KMT2AHSP90AA1ATMNPC1
SCHEMBL23242992 0.83 ATM (0.68) MEN1KMT2AHSP90AA1ATMNPC1
SCHEMBL10480070 0.83 ATM (0.68) MEN1KMT2AHSP90AA1ATMNPC1
Dimethylamine SCHEMBL11508825 0.76 MAPK1 (0.59) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL20237291 0.74 MEN1 (0.50) MEN1KMT2AHSP90AA1ATMNPC1
SCHEMBL20237292 0.74 MEN1 (0.50) MEN1KMT2AHSP90AA1ATMNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7754295-B2 Single substrate guest-host polymer dispersed liquid crystal displays INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2010-07-13 — — US claimed
WO-2008005202-A2 SINGLE SUBSTRATE GUEST-HOST POLYMER LIQUID CRYSTAL DISPLAYS INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2008-01-10 — — WO claimed
US-20080003379-A1 electronically modulated imaging layer comprises a dichroic or pleochroic dye in a fixed latex polymer matrix; low cost; display having excellent brightness, high contrast, and low switching voltage EASTMAN KODAK COMPANY 2008-01-03 — — US claimed
US-7754295-B2 Single substrate guest-host polymer dispersed liquid crystal displays INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2010-07-13 — — US disclosed
WO-2008005202-A2 SINGLE SUBSTRATE GUEST-HOST POLYMER LIQUID CRYSTAL DISPLAYS INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2008-01-10 — — WO disclosed
US-20080003379-A1 electronically modulated imaging layer comprises a dichroic or pleochroic dye in a fixed latex polymer matrix; low cost; display having excellent brightness, high contrast, and low switching voltage EASTMAN KODAK COMPANY 2008-01-03 — — US disclosed
US-4179395-A LIQUID CRYSTALS FOR USE IN DISPLAYS GENERAL ELECTRIC COMPANY (US) 1979-12-18 — — US disclosed
US-4128497-A TRISAZO DYE GENERAL ELECTRIC COMPANY (US) 1978-12-05 — — US disclosed
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