Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.68 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10480070 | 1.00 | ATM (0.68) | ATMMEN1KMT2AHSP90AA1CYP2A6 | |
| SCHEMBL11224625 | 0.85 | ATM (0.54) | ATMMEN1KMT2AHSP90AA1CYP2A6 | |
| SCHEMBL11224623 | 0.85 | ATM (0.54) | ATMMEN1KMT2AHSP90AA1CYP2A6 | |
| SCHEMBL16594280 | 0.84 | ALDH1A1 (0.57) | ATMMEN1KMT2AHSP90AA1ACHE | |
| SCHEMBL16594278 | 0.84 | ALDH1A1 (0.57) | ATMMEN1KMT2AHSP90AA1ACHE | |
| SCHEMBL19336625 | 0.83 | ATM (0.52) | ATMMEN1KMT2AHSP90AA1CYP2A6 | |
| Dimethylamine SCHEMBL3693873 | 0.83 | MEN1 (0.52) | ATMMEN1KMT2AHSP90AA1CYP2A6 | |
| SCHEMBL11151430 | 0.79 | MEN1 (0.64) | ATMMEN1KMT2AHSP90AA1ALDH1A1 | |
| SCHEMBL11151415 | 0.79 | MEN1 (0.64) | ATMMEN1KMT2AHSP90AA1ALDH1A1 | |
| SCHEMBL7937665 | 0.79 | ATM (0.48) | ATMMEN1KMT2AHSP90AA1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997139-B | Synthetic method of 3,3',5,5' -tetramethyl benzidine and hydrochloride thereof | 南京艾普特生物医药有限公司 | 2020-11-10 | — | — | CN | claimed |
| CN-108997139-A | A kind of synthetic method of 3,3`, 5,5`- tetramethyl benzidine and its hydrochloride | 南京艾普特生物医药有限公司 | 2018-12-14 | — | — | CN | claimed |
| US-11028044-B2 | Versatile, concise and convenient process for the commercial scale preparation of highest pure 3,3′5,5′-tetramethylbenzidine (TMB) and its salts, a chromogenic substrate used in staining procedures in immunohistochemistry and visualizing reagent in enzyme-linked immunosorbent assays | SLR Biosciences, LLC (US) | 2021-06-08 | — | — | US | disclosed |
| US-11028044-B2 | Versatile, concise and convenient process for the commercial scale preparation of highest pure 3,3′5,5′-tetramethylbenzidine (TMB) and its salts, a chromogenic substrate used in staining procedures in immunohistochemistry and visualizing reagent in enzyme-linked immunosorbent assays | SLR Biosciences, LLC (US) | 2021-06-08 | — | — | US | disclosed |
| US-20210114974-A1 | Versatile, concise and convenient process for the commercial scale preparation of highest pure 3,3'5,5'-Tetramethylbenzidine (TMB) and its salts, a chromogenic substrate used in staining procedures in immunohistochemistry and visualizing reagent in enzyme-linked immunosorbent assays | SLR Biosciences, LLC (US) | 2021-04-22 | — | — | US | disclosed |
| US-20210114974-A1 | Versatile, concise and convenient process for the commercial scale preparation of highest pure 3,3'5,5'-Tetramethylbenzidine (TMB) and its salts, a chromogenic substrate used in staining procedures in immunohistochemistry and visualizing reagent in enzyme-linked immunosorbent assays | SLR Biosciences, LLC (US) | 2021-04-22 | — | — | US | disclosed |
| CN-108997139-B | Synthetic method of 3,3',5,5' -tetramethyl benzidine and hydrochloride thereof | 南京艾普特生物医药有限公司 | 2020-11-10 | — | — | CN | disclosed |
| CN-108997139-A | A kind of synthetic method of 3,3`, 5,5`- tetramethyl benzidine and its hydrochloride | 南京艾普特生物医药有限公司 | 2018-12-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210114974-A1 | Versatile, concise and convenient process for the commercial scale preparation of highest pure 3,3'5,5'-Tetramethylbenzidine (TMB) and its salts, a chromogenic substrate used in staining procedures in immunohistochemistry and visualizing reagent in enzyme-linked immunosorbent assays | BTD, MPO, TPO | ATM 2008/4885MEN1 1983/4885KMT2A 3254/4885 |
| US-11028044-B2 | Versatile, concise and convenient process for the commercial scale preparation of highest pure 3,3′5,5′-tetramethylbenzidine (TMB) and its salts, a chromogenic substrate used in staining procedures in immunohistochemistry and visualizing reagent in enzyme-linked immunosorbent assays | BTD, MPO, TPO | ATM 1963/4885MEN1 2017/4885KMT2A 3203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.