Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3649894 | 1.00 | MEN1 (0.38) | MEN1MAPK1KMT2ANFKB1NFKB2 | |
| SCHEMBL1636481 | 1.00 | MEN1 (0.38) | MEN1MAPK1KMT2ANFKB1NFKB2 | |
| SCHEMBL28049898 | 0.81 | MEN1 (0.37) | MEN1MAPK1KMT2ANFKB1NFKB2 | |
| SCHEMBL3361308 | 0.81 | MEN1 (0.37) | MEN1MAPK1KMT2ANFKB1NFKB2 | |
| SCHEMBL4383932 | 0.78 | KMT2A (0.37) | MEN1MAPK1KMT2ANFKB1NFKB2 | |
| SCHEMBL7936343 | 0.73 | KMT2A (0.39) | MEN1MAPK1KMT2ANFKB1NFKB2 | |
| SCHEMBL1635700 | 0.73 | KMT2A (0.39) | MEN1MAPK1KMT2ANFKB1NFKB2 | |
| SCHEMBL3645354 | 0.73 | KMT2A (0.39) | MEN1MAPK1KMT2ANFKB1NFKB2 | |
| SCHEMBL15125116 | 0.73 | KMT2A (0.39) | MEN1MAPK1KMT2ANFKB1NFKB2 | |
| SCHEMBL1636480 | 0.73 | KMT2A (0.39) | MEN1MAPK1KMT2ANFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185524-A1 | NOVEL PEPTIDE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | Intermune, Inc. (US) | 2010-05-19 | — | — | EP | disclosed |
| WO-2008141227-A1 | NOVEL PEPTIDE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2008-11-20 | — | — | WO | disclosed |