Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2889149 | 0.86 | TP53 (0.54) | ABL1MAPTRAB9ANPC1PYGL | |
| SCHEMBL7126697 | 0.77 | KDM4E (0.56) | ABL1MAPTRAB9ANPC1ATM | |
| SCHEMBL2884838 | 0.76 | ALDH1A1 (0.47) | ABL1MAPTRAB9ANPC1ATM | |
| SCHEMBL17772042 | 0.73 | ABL1 (0.57) | ABL1MAPTRAB9ANPC1ATM | |
| SCHEMBL4854740 | 0.72 | ABL1 (0.60) | ABL1MAPTRAB9ANPC1ATM | |
| SCHEMBL231538 | 0.72 | ABL1 (0.49) | ABL1MAPTRAB9ANPC1ATM | |
| SCHEMBL1290704 | 0.71 | KDM4E (0.60) | ABL1MAPTRAB9ANPC1ATM | |
| SCHEMBL6654858 | 0.71 | SRD5A2 (0.70) | MAPTRAB9ANPC1CYP1A2CYP2C19 | |
| SCHEMBL11590852 | 0.71 | POLB (0.67) | MAPTRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL7908252 | 0.70 | CA1 (0.57) | MAPTRAB9AATMCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185504-A2 | BIS-AROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009030887-A2 | BIS-AROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2009-03-12 | — | — | WO | disclosed |