Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3694429 | 1.00 | L3MBTL1 (0.43) | L3MBTL1MEN1KMT2ATDP1MAPT | |
| SCHEMBL3309044 | 0.77 | MEN1 (0.47) | L3MBTL1MEN1KMT2ATDP1MAPT | |
| SCHEMBL3309052 | 0.77 | MEN1 (0.47) | L3MBTL1MEN1KMT2ATDP1MAPT | |
| SCHEMBL3306009 | 0.74 | L3MBTL1 (0.46) | L3MBTL1MEN1KMT2ATDP1MAPT | |
| SCHEMBL3306000 | 0.74 | L3MBTL1 (0.46) | L3MBTL1MEN1KMT2ATDP1MAPT | |
| SCHEMBL21451609 | 0.73 | L3MBTL1 (0.44) | L3MBTL1MEN1KMT2ATDP1MAPT | |
| SCHEMBL148563 | 0.67 | ALDH1A1 (0.35) | LMNAALDH1A1HPGD | |
| SCHEMBL152263 | 0.67 | ALDH1A1 (0.35) | LMNAALDH1A1HPGD | |
| SCHEMBL148562 | 0.67 | ALDH1A1 (0.35) | LMNAALDH1A1HPGD | |
| SCHEMBL30595741 | 0.66 | CES1 (0.37) | MEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2452938-A1 | Process for the preparation of 3-aroyl-5-aminobenzofuran derivatives | LEK Pharmaceuticals d.d. (SI) | 2012-05-16 | — | — | EP | disclosed |