Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 3/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | PLAU | P00749 | 2/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2851292 | 1.00 | L3MBTL1 (0.51) | L3MBTL1ELANEF2PLAUCTRB1 | |
| SCHEMBL13854989 | 0.89 | L3MBTL1 (0.61) | L3MBTL1ELANEF2PLAUCTRB1 | |
| SCHEMBL2848565 | 0.86 | ELANE (0.61) | L3MBTL1ELANEF2PLAUCTRB1 | |
| SCHEMBL2845665 | 0.85 | ELANE (0.47) | L3MBTL1ELANEF2PLAUCTRB1 | |
| SCHEMBL31554629 | 0.84 | L3MBTL1 (0.47) | L3MBTL1ELANEF2PLAUCTRB1 | |
| SCHEMBL11153081 | 0.82 | L3MBTL1 (0.45) | L3MBTL1ELANEF2PLAUCTRB1 | |
| SCHEMBL2843483 | 0.82 | MAPT (0.51) | L3MBTL1ELANEF2PLAUCTRB1 | |
| SCHEMBL14909376 | 0.81 | L3MBTL1 (0.51) | L3MBTL1ELANEF2PLAUCTRB1 | |
| SCHEMBL3380500 | 0.79 | L3MBTL1 (0.52) | L3MBTL1ELANEF2PLAUCTRB1 | |
| SCHEMBL31554652 | 0.79 | L3MBTL1 (0.47) | L3MBTL1ELANEF2PLAUCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185572-A1 | SUBSTITUTED ARYLSULFONYLAMINOMETHYLPHOSPHONIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF TYPE I AND II DIABETES MELLITUS | Boehringer Ingelheim International GmbH (DE) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009016119-A1 | SUBSTITUTED ARYLSULFONYLAMINOMETHYLPHOSPHONIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF TYPE I AND II DIABETES MELLITUS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-02-05 | — | — | WO | disclosed |