Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | ELANE | P08246 | 5/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.53 |
| ▸ | PLAU | P00749 | 2/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.53 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | F2R | P25116 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2851292 | 0.89 | L3MBTL1 (0.51) | L3MBTL1ELANEF2PLAUCTRB1 | |
| SCHEMBL3694723 | 0.89 | L3MBTL1 (0.51) | L3MBTL1ELANEF2PLAUCTRB1 | |
| SCHEMBL31482827 | 0.89 | L3MBTL1 (0.58) | L3MBTL1ELANEF2PLAUCTRB1 | |
| SCHEMBL13854988 | 0.86 | ELANE (0.67) | L3MBTL1ELANEF2PLAUCTRB1 | |
| SCHEMBL13854991 | 0.84 | L3MBTL1 (0.53) | L3MBTL1ELANEF2PLAUCTRB1 | |
| SCHEMBL961818 | 0.82 | ELANE (0.52) | L3MBTL1ELANEF2PLAUCTRB1 | |
| SCHEMBL11145800 | 0.82 | L3MBTL1 (0.54) | L3MBTL1ELANEF2PLAUCTRB1 | |
| SCHEMBL27730179 | 0.82 | ELANE (0.53) | L3MBTL1ELANEF2PLAUCTRB1 | |
| SCHEMBL13854990 | 0.81 | L3MBTL1 (0.50) | L3MBTL1ELANEF2PLAUCTRB1 | |
| SCHEMBL14908618 | 0.81 | L3MBTL1 (0.62) | L3MBTL1ELANEF2PLAUCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8546404-B2 | Compounds that are ERK inhibitors | MERCK SHARP & DOHME (US) | 2013-10-01 | — | — | US | disclosed |
| US-20090118284-A1 | Novel compounds that are ERK inhibitors | MERCK SHARP & DOHME LLC | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118284-A1 | Novel compounds that are ERK inhibitors | MAPK1, MAPK4, MAPK10 | L3MBTL1 3535/4885ELANE 3367/4885F2 4355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.