Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 4/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL1080950 | 0.91 | PTGES (0.38) | PTGESMAOBACKR3C3AR1CHRM2 | |
| SCHEMBL1178170 | 0.90 | PTGES (0.48) | PTGESPTGS2MAOBC3AR1 | |
| SCHEMBL1080947 | 0.90 | PTGES (0.38) | PTGESMAOBACKR3C3AR1CHRM2 | |
| SCHEMBL1178056 | 0.89 | PTGES (0.42) | PTGESMAOBACKR3ITGB3ITGA2B | |
| SCHEMBL1178655 | 0.86 | PTGES (0.34) | PTGESMAOBACKR3C3AR1CHRM2 | |
| SCHEMBL1178336 | 0.84 | MAOB (0.34) | MAOBC3AR1CHRM2CHRM1CHRM3 | |
| SCHEMBL1079856 | 0.82 | PTGES (0.45) | PTGESPTGS2MAOBACKR3 | |
| SCHEMBL3693615 | 0.82 | ITGB3 (0.36) | MAOBACKR3ITGB3ITGA2B | |
| SCHEMBL1178131 | 0.81 | PTGES (0.42) | PTGESPTGS2MAOB | |
| SCHEMBL1178561 | 0.81 | PTGES (0.46) | PTGESPTGS2MAOBACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-B1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Pharma AG (DE) | 2012-05-16 | — | — | EP | disclosed |