Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | PTGIR | P43119 | 2/20 | 0.47 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3691723 | 0.92 | PTGDR2 (0.53) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL3695869 | 0.84 | PTGDR2 (0.43) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL3693923 | 0.81 | PTGDR2 (0.47) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL3391526 | 0.80 | PTGDR2 (0.58) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL3704364 | 0.80 | L3MBTL1 (0.40) | CYP3A4CYP2C9MEN1KMT2A | |
| SCHEMBL3411657 | 0.80 | PTGDR2 (0.46) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL3694447 | 0.77 | L3MBTL1 (0.41) | CYP3A4CYP2C9MEN1KMT2A | |
| SCHEMBL27986022 | 0.76 | PTGDR2 (0.58) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL2502913 | 0.74 | PTGDR2 (0.76) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL28785867 | 0.73 | PTGDR2 (0.50) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042652-A2 | HETEROALKYL BIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-04-15 | — | — | WO | disclosed |