Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258581 | 0.91 | ALDH1A1 (0.42) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL149809 | 0.89 | RAB9A (0.40) | SERPINE1ALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL3709326 | 0.89 | ALDH1A1 (0.34) | SERPINE1ALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL201767 | 0.87 | EPHX1 (0.42) | ALDH1A1EPHX1TSHRNAAA | |
| SCHEMBL10645478 | 0.87 | EPHX1 (0.42) | ALDH1A1EPHX1TSHRNAAA | |
| SCHEMBL36619 | 0.87 | EPHX1 (0.42) | ALDH1A1EPHX1TSHRNAAA | |
| SCHEMBL687414 | 0.87 | ALDH1A1 (0.46) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL13431240 | 0.86 | BTK (0.39) | SERPINE1ALDH1A1TSHR | |
| SCHEMBL887989 | 0.85 | EPHX1 (0.46) | ALDH1A1EPHX1NAAA | |
| SCHEMBL18822970 | 0.85 | EPHX1 (0.46) | ALDH1A1EPHX1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140343222-A1 | POLY(LACTONE)S, METHOD OF MANUFACTURE, AND USES THEREOF | SEGETIS, INC (US) | 2014-11-20 | — | — | US | disclosed |
| US-8846817-B2 | Ionic polymers, method of manufacture, and uses thereof | SEGETIS, INC. (US) | 2014-09-30 | — | — | US | disclosed |
| EP-2776491-A1 | POLY(LACTONE)S, METHOD OF MANUFACTURE, AND USES THEREOF | Segetis, Inc. (US) | 2014-09-17 | — | — | EP | disclosed |
| CN-103210014-A | Ionic polymers, method for producing same and use thereof | SEGETIS INC | 2013-07-17 | — | — | CN | disclosed |
| WO-2013071256-A1 | POLY(LACTONE)S, METHOD OF MANUFACTURE, AND USES THEREOF | SEGETIS, INC. (US) | 2013-05-16 | — | — | WO | disclosed |
| US-20120118832-A1 | IONIC POLYMERS, METHOD OF MANUFACTURE, AND USES THEREOF | SEGETIS, INC. (US) | 2012-05-17 | — | — | US | disclosed |