Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28365601 | 0.84 | MAPT (0.53) | MAPTALOX5ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL619380 | 0.81 | MAPT (0.78) | MAPTALOX5ALDH1A1MEN1KMT2A | |
| SCHEMBL30719041 | 0.81 | MAPT (0.78) | MAPTALOX5ALDH1A1MEN1KMT2A | |
| SCHEMBL7954034 | 0.79 | MAPT (0.48) | MAPTALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL28480400 | 0.79 | MAPT (0.53) | MAPTALOX5ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL30719117 | 0.77 | MAPT (0.55) | MAPTALOX5ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL30933981 | 0.77 | MAPT (0.46) | MAPTALOX5ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL10529318 | 0.77 | WDR5 (0.49) | MAPTALOX5ALDH1A1TDP1WDR5 | |
| SCHEMBL16891251 | 0.75 | MAPT (0.49) | MAPTALOX5ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL30719008 | 0.75 | NPC1 (0.59) | MAPTALOX5ALDH1A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120981-A1 | ETHYLENE COPOLYMER AND A METHOD OF PREPARING THE SAME | SABIC SK NEXLENE COMPANY PTE. LTD. (SG) | 2010-05-13 | — | — | US | disclosed |