SCHEMBL369672

SCHEMBL369672

C=CCNc1ncnc(NCC=C)n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.44
KMT2A Q03164 3/20 0.44
GAA P10253 2/20 0.44
RAB9A P51151 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MEN1 O00255 2/20 0.44
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
HPGD P15428 1/20 0.41
MTOR P42345 1/20 0.41
HTT P42858 1/20 0.41
NCOA1 Q15788 1/20 0.41
NCOA3 Q9Y6Q9 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MAPK1 P28482 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10866329 0.86 MAPT (0.39) MAPTKMT2AGAARAB9ASMN1; SMN2
SCHEMBL727149 0.86 SMN1; SMN2 (0.45) MAPTKMT2AGAARAB9ASMN1; SMN2
SCHEMBL11058935 0.86 MAPT (0.39) MAPTKMT2AGAARAB9ASMN1; SMN2
SCHEMBL7741690 0.86 ALDH1A1 (0.50) MAPTKMT2AGAARAB9ASMN1; SMN2
SCHEMBL11787512 0.86 MAPT (0.39) MAPTKMT2AGAARAB9ASMN1; SMN2
SCHEMBL3237315 0.83 GAA (0.53) MAPTKMT2AGAARAB9ASMN1; SMN2
SCHEMBL88752 0.82 MAPT (0.41) MAPTKMT2AGAARAB9ASMN1; SMN2
SCHEMBL368087 0.82 GAA (0.59) MAPTKMT2AGAARAB9ASMN1; SMN2
SCHEMBL369459 0.80 KMT2A (0.44) MAPTKMT2AGAARAB9ASMN1; SMN2
SCHEMBL8138105 0.75 MAPT (0.37) MAPTKMT2AGAARAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0012717-A1 Method and composition for the selective pre-emergent control of weeds in cereal cultures CIBA-GEIGY AG (CH) 1980-06-25 EP claimed
EP-2407460-B1 N-TRIAZINYLAMMONIUM SALTS, A METHOD OF PREPARATION AND USES THEREOF POLITECHNIKA LODZKA (PL) 2013-07-17 EP disclosed
EP-2407460-A1 N-Triazinylammonium salts, a method of preparation and uses thereof Politechnika Lódzka (PL) 2012-01-18 EP disclosed
US-20100292469-A1 PROCESS FOR THE PREPARATION OF N-TRIAZINYLAMMONIUM SALTS ITALVELLUTI S.P.A. (IT) 2010-11-18 US disclosed
EP-1951691-A1 PROCESS FOR THE PREPARATION OF N-TRIAZINYLAMMONIUM SALTS Italvelluti S.p.A. (IT) 2008-08-06 EP disclosed
WO-2007051496-A1 PROCESS FOR THE PREPARATION OF N-TRIAZINYLAMMONIUM SALTS ITALVELLUTI S.P.A. (IT) 2007-05-10 WO disclosed
EP-0214507-B1 OUTDOOR FILMS STABILIZED AGAINST CHEMICAL ATTACK AMERICAN CYANAMID COMPANY (US) 1992-01-15 EP disclosed
EP-0012717-B1 METHOD AND COMPOSITION FOR THE SELECTIVE PRE-EMERGENT CONTROL OF WEEDS IN CEREAL CULTURES CIBA-GEIGY AG (CH) 1983-01-26 EP disclosed
US-4309210-A HERBICIDE AND SAFENING AGENT CIBA-GEIGY CORPORATION (US) 1982-01-05 US disclosed
US-4275204-A STEP-WISE REACTION WITH AMINES AND CYANURIC CHLORIDE IN WATER SOLVENTS AND ALKALI METAL HYDROXIDE RUMIANCA S.P.A. (IT) 1981-06-23 US disclosed
US-4224444-A STEP-WISE REPLACEMENT OF TWO CHLORINE ATOMS FROM CYANURIC CHLORIDE RUMIANCA S.P.A. (IT) 1980-09-23 US disclosed
EP-0012717-A1 Method and composition for the selective pre-emergent control of weeds in cereal cultures CIBA-GEIGY AG (CH) 1980-06-25 EP disclosed