SCHEMBL727149

SCHEMBL727149

C=CCNc1ncnc(N)n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.45
BCL6 P41182 1/20 0.43
RAB9A P51151 2/20 0.41
ADORA3 P0DMS8 1/20 0.41
SLC6A2 P23975 1/20 0.41
PDE4A P27815 1/20 0.41
KDR P35968 1/20 0.41
MAPT P10636 2/20 0.40
GAA P10253 3/20 0.39
HTT P42858 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
KDM4E B2RXH2 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
LMNA P02545 2/20 0.37
ALDH1A1 P00352 2/20 0.36
HPGD P15428 1/20 0.36
MTOR P42345 1/20 0.36
NCOA1 Q15788 1/20 0.36
NCOA3 Q9Y6Q9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL369672 0.86 MAPT (0.44) SMN1; SMN2RAB9AKDRMAPTGAA
SCHEMBL4736866 0.81 SMN1; SMN2 (0.42) SMN1; SMN2BCL6RAB9AADORA3SLC6A2
SCHEMBL2268712 0.78 POLB (0.46) SMN1; SMN2RAB9AMAPTGAAHTT
SCHEMBL276285 0.78 GAA (0.46) MAPTGAAMEN1KMT2AALDH1A1
SCHEMBL11787512 0.78 MAPT (0.39) SMN1; SMN2RAB9AKDRMAPTGAA
SCHEMBL10866329 0.78 MAPT (0.39) SMN1; SMN2RAB9AKDRMAPTGAA
SCHEMBL7741690 0.78 ALDH1A1 (0.50) SMN1; SMN2RAB9AKDRMAPTGAA
SCHEMBL11058935 0.78 MAPT (0.39) SMN1; SMN2RAB9AKDRMAPTGAA
SCHEMBL14346807 0.75 SMN1; SMN2 (0.57) SMN1; SMN2BCL6RAB9AADORA3SLC6A2
Formaldehyde SCHEMBL5690331 0.75 GAA (0.43) SMN1; SMN2MAPTGAAHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4733269-B2 2011-07-27 JP claimed
US-20040171489-A1 Synergistic active compound combinations for controlling harmful plants BAYER INTELLECTUAL PROPERTY GMBH (DE) 2004-09-02 US claimed
CN-1113060-C Substituted 2-amino-4-alkylamino-1, 3, 5-triazines as herbicides BAYER AG (DE) 2003-07-02 CN claimed
US-6346503-B1 PRE- AND POSTEMERGENCE HERBICIDES FOR CROPS LIKE CORN, WHEAT, AND COTTON BAYER AKTIENGESELLSCHAFT (DE) 2002-02-12 US claimed
US-20020016459-A1 Substituted 2-amino-4-alkylamino-1,3,5-triazines as herbicides RIEBEL HANS-JOCHEM (DE) 2002-02-07 US claimed
US-6284710-B1 CONTROLLING WEEDS BAYER AKTIENGESELLSCHAFT (DE) 2001-09-04 US claimed
EP-1113720-A1 SYNERGISTIC ACTIVE SUBSTANCE COMBINATIONS FOR CONTROLLING HARMFUL PLANTS Aventis CropScience GmbH (DE) 2001-07-11 EP claimed
WO-2000016627-A1 SYNERGISTIC ACTIVE SUBSTANCE COMBINATIONS FOR CONTROLLING HARMFUL PLANTS AVENTIS CROPSCIENCE GMBH (DE) 2000-03-30 WO claimed
EP-0934285-A1 SUBSTITUTING 2-AMINO-4-ALKYLAMINO-1,3,5-TRIAZINE AS HERBICIDE BAYER AG (DE) 1999-08-11 EP claimed
EP-0934284-A1 SUBSTITUTED 2-AMINO-4-ALKYLAMINO-1,3,5-TRIAZINES AS HERBICIDES BAYER AG (DE) 1999-08-11 EP claimed
WO-1998015537-A1 SUBSTITUTED 2-AMINO-4-ALKYLAMINO-1,3,5-TRIAZINES AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-04-16 WO claimed
WO-1998015539-A1 SUBSTITUTING 2-AMINO-4-ALKYLAMINO-1,3,5-TRIAZINE AS HERBICIDE BAYER AKTIENGESELLSCHAFT (DE) 1998-04-16 WO claimed
US-20040171489-A1 Synergistic active compound combinations for controlling harmful plants BAYER INTELLECTUAL PROPERTY GMBH (DE) 2004-09-02 US disclosed
CN-1113060-C Substituted 2-amino-4-alkylamino-1, 3, 5-triazines as herbicides BAYER AG (DE) 2003-07-02 CN disclosed
CN-1113060-C Substituted 2-amino-4-alkylamino-1, 3, 5-triazines as herbicides BAYER AG (DE) 2003-07-02 CN disclosed
CN-1113060-C Substituted 2-amino-4-alkylamino-1, 3, 5-triazines as herbicides BAYER AG (DE) 2003-07-02 CN disclosed
WO-1998015537-A1 SUBSTITUTED 2-AMINO-4-ALKYLAMINO-1,3,5-TRIAZINES AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-04-16 WO disclosed
WO-1998015537-A1 SUBSTITUTED 2-AMINO-4-ALKYLAMINO-1,3,5-TRIAZINES AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-04-16 WO disclosed
WO-1998015537-A1 SUBSTITUTED 2-AMINO-4-ALKYLAMINO-1,3,5-TRIAZINES AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-04-16 WO disclosed
US-4113947-A WASH RESISTANT WATER REPELLEMT FINISH FOR FIBERS CIBA-GEIGY CORPORATION (US) 1978-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020016459-A1 Substituted 2-amino-4-alkylamino-1,3,5-triazines as herbicides AHR, DDT, CYP1A1 SMN1; SMN2 3294/4885BCL6 1803/4885RAB9A 3092/4885
US-20040171489-A1 Synergistic active compound combinations for controlling harmful plants L3MBTL4, TTL, EBPL SMN1; SMN2 3808/4885BCL6 4349/4885RAB9A 4583/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.