Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.53 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 6/20 | 0.51 |
| ▸ | ACHE | P22303 | 5/20 | 0.51 |
| ▸ | F3 | P13726 | 1/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6050471 | 1.00 | MAOB (0.60) | MAOBMAPTMEN1KMT2ALMNA | |
| SCHEMBL3694613 | 0.83 | ABCG2 (0.62) | MAPTMEN1KMT2ALMNATNFRSF1A | |
| SCHEMBL6050485 | 0.83 | MAPT (0.59) | MAPTLMNATNFRSF1AALDH1A1 | |
| SCHEMBL3695218 | 0.83 | MAPT (0.59) | MAPTLMNATNFRSF1AALDH1A1 | |
| SCHEMBL3690293 | 0.83 | ABCG2 (0.62) | MAPTMEN1KMT2ALMNATNFRSF1A | |
| SCHEMBL3682208 | 0.82 | LMNA (0.50) | MAOBMAPTMEN1KMT2ALMNA | |
| SCHEMBL5915740 | 0.82 | MAOB (0.61) | MAOBMAPTMEN1KMT2ALMNA | |
| SCHEMBL3685701 | 0.81 | MAOB (0.55) | MAOBMAPTMEN1KMT2ALMNA | |
| SCHEMBL3696884 | 0.79 | MAOB (0.60) | MAOBMAPTMEN1KMT2ALMNA | |
| SCHEMBL3691415 | 0.77 | TNFRSF1A (0.50) | MAOBTNFRSF1AALDH1A1CYP1B1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642367-B2 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2010-01-05 | — | — | US | disclosed |
| US-20060235073-A1 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-10-19 | — | — | US | disclosed |