Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | YAP1 | P46937 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15092140 | 0.91 | YAP1 (0.37) | TLR9TLR7YAP1MEN1KMT2A | |
| SCHEMBL15097407 | 0.82 | LMNA (0.34) | MEN1KMT2ANAPEPLD | |
| SCHEMBL368710 | 0.82 | TLR9 (0.40) | TLR9TLR7ACHEYAP1MEN1 | |
| SCHEMBL369124 | 0.82 | TLR9 (0.37) | TLR9TLR7YAP1MEN1KMT2A | |
| SCHEMBL369852 | 0.81 | TLR9 (0.41) | TLR9TLR7ACHEYAP1MEN1 | |
| SCHEMBL367643 | 0.80 | TP53 (0.39) | TLR9YAP1MEN1KMT2A | |
| SCHEMBL15101376 | 0.80 | PDE4B (0.39) | GPR119 | |
| SCHEMBL369242 | 0.80 | TLR9 (0.40) | TLR9TLR7ACHEYAP1MEN1 | |
| SCHEMBL369125 | 0.78 | PRMT5 (0.41) | TLR9TLR7ACHEYAP1GPR119 | |
| SCHEMBL15092068 | 0.78 | TLR9 (0.43) | TLR9TLR7ACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593460-A1 | 7, 9-NITROGEN RADICAL-4-OXO-4H-PYRIDO[L,2-A]PYRIMIDINE-2-CARBOXYLIC ACID BENZYLAMIDE ANTI-VIRALS | Avexa Limited (AU) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012006680-A1 | 7, 9-NITROGEN RADICAL-4-OXO-4H-PYRIDO[L,2-A]PYRIMIDINE-2-CARBOXYLIC ACID BENZYLAMIDE ANTI-VIRALS | AVEXA LIMITED (AU) | 2012-01-19 | — | — | WO | disclosed |