Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5651810 | 0.82 | MTNR1A (0.50) | MTNR1AMTNR1BROCK2LMNAKDM4E | |
| SCHEMBL5651807 | 0.70 | MTNR1A (0.50) | MTNR1AMTNR1BROCK2LMNAKDM4E | |
| SCHEMBL3688184 | 0.69 | ROCK2 (0.54) | MTNR1AMTNR1BROCK2LMNAKDM4E | |
| SCHEMBL3690391 | 0.68 | KCNH2 (0.49) | MTNR1AMTNR1BROCK2LMNAKCNH2 | |
| SCHEMBL4081621 | 0.68 | MTNR1A (0.64) | MTNR1AMTNR1BROCK2LMNAKDM4E | |
| SCHEMBL12776123 | 0.67 | MTNR1A (0.55) | MTNR1AMTNR1BROCK2LMNAKDM4E | |
| SCHEMBL13145890 | 0.67 | KCNH2 (0.49) | MTNR1AMTNR1BKCNH2 | |
| SCHEMBL2544860 | 0.67 | MTNR1A (0.61) | MTNR1AMTNR1BROCK2LMNAKDM4E | |
| SCHEMBL5651333 | 0.66 | KCNH2 (0.48) | MTNR1AMTNR1BROCK2KCNH2 | |
| Bromide SCHEMBL30402372 | 0.66 | MTNR1A (0.60) | MTNR1AMTNR1BROCK2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2239260-A1 | Novel compounds with antibacterial activity | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2010-10-13 | — | — | EP | disclosed |
| EP-1551829-A2 | NOVEL COMPOUNDS WITH ANTIBACTERIAL ACTIVITY | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004035569-A2 | NOVEL COMPOUNDS WITH ANTIBACTERIAL ACTIVITY | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2004-04-29 | — | — | WO | disclosed |