Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 5/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 5/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | GLS | O94925 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3695801 | 0.91 | HTR2C (0.38) | HTR2CSLC6A4HTR2ARIPK1F2 | |
| SCHEMBL4127061 | 0.88 | SLC16A3 (0.34) | SLC16A3SLC16A1HTR6KEAP1 | |
| SCHEMBL3700004 | 0.88 | HTR2C (0.39) | HTR2CSLC6A4HTR2ASLC16A3SLC16A1 | |
| SCHEMBL3699024 | 0.88 | HTR2C (0.46) | HTR2CSLC6A4HTR2ASLC16A3SLC16A1 | |
| SCHEMBL3700738 | 0.88 | HTR2C (0.44) | HTR2CSLC6A4HTR2ASLC16A3SLC16A1 | |
| SCHEMBL3808572 | 0.85 | HTR2C (0.41) | HTR2CSLC6A4HTR2ASLC16A3SLC16A1 | |
| SCHEMBL3699812 | 0.84 | HTR2C (0.38) | HTR2CSLC6A4HTR2ARIPK1F2 | |
| SCHEMBL4200021 | 0.83 | HTR2C (0.36) | HTR2CSLC6A4HTR2ASLC16A3SLC16A1 | |
| SCHEMBL3700608 | 0.83 | HTR2C (0.40) | HTR2CSLC6A4HTR2ASLC16A3SLC16A1 | |
| SCHEMBL3697997 | 0.82 | HTR2C (0.41) | HTR2CSLC6A4HTR2ASLC16A3SLC16A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009041705-A9 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2009-08-13 | — | — | WO | disclosed |
| WO-2009041705-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-02 | — | — | WO | disclosed |