Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 4/20 | 0.34 |
| ▸ | SLC16A1 | P53985 | 4/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | LIMK2 | P53671 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4130995 | 0.91 | NAMPT (0.36) | — | |
| SCHEMBL3697137 | 0.88 | HTR2C (0.44) | SLC16A3SLC16A1KEAP1HTR6 | |
| SCHEMBL4135632 | 0.88 | PTGS2 (0.32) | SLC16A3SLC16A1LIMK2ALDH1A1LMNA | |
| SCHEMBL3693029 | 0.87 | ALDH1A1 (0.39) | SLC16A3SLC16A1LIMK2ALDH1A1LMNA | |
| SCHEMBL4125913 | 0.86 | KMT2A (0.36) | HTR6LIMK2KMT2AMAPT | |
| SCHEMBL4126123 | 0.86 | NAMPT (0.35) | SLC16A3SLC16A1HTR6ALDH1A1KMT2A | |
| SCHEMBL3697140 | 0.85 | SLC16A3 (0.34) | SLC16A3SLC16A1HTR6LMNAKMT2A | |
| SCHEMBL4131198 | 0.84 | NAMPT (0.39) | SLC16A3SLC16A1ALDH1A1LMNAKDM4E | |
| SCHEMBL4125804 | 0.83 | NAMPT (0.36) | KEAP1MAPTSMN1; SMN2 | |
| SCHEMBL4130428 | 0.82 | SLC16A3 (0.34) | SLC16A3SLC16A1LIMK2SCN3ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-B1 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2014-12-31 | — | — | EP | disclosed |
| US-20090156642-A1 | 5-Membered heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156642-A1 | 5-Membered heterocyclic compound | CEL, PGA5, COG5 | SLC16A3 2809/4885SLC16A1 2925/4885KEAP1 1892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.