⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1234039 | 0.87 | — | — | |
| SCHEMBL1234496 | 0.80 | CYP11B2 (0.35) | — | |
| SCHEMBL1234239 | 0.80 | — | — | |
| SCHEMBL1234294 | 0.79 | CNR1 (0.33) | — | |
| SCHEMBL1233841 | 0.76 | — | — | |
| SCHEMBL1234305 | 0.76 | — | — | |
| SCHEMBL1233633 | 0.75 | GAA (0.30) | — | |
| SCHEMBL3701526 | 0.73 | ALDH1A1 (0.32) | — | |
| SCHEMBL1233831 | 0.72 | MEN1 (0.30) | — | |
| SCHEMBL1234280 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696912-B1 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2016-05-11 | — | — | EP | disclosed |
| US-9145410-B2 | Pyrazolopyridines and analogs thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-09-29 | — | — | US | disclosed |
| US-20120121651-A1 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | 3M INNOVATIVE PROPERTIES COMPANY | 2012-05-17 | — | — | US | disclosed |