Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.55 |
| ▸ | SRC | P12931 | 3/20 | 0.55 |
| ▸ | PLK1 | P53350 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325858 | 0.80 | IDO1 (0.56) | EGFRSRCKDM4EIDO1L3MBTL1 | |
| SCHEMBL371112 | 0.79 | IDO1 (0.51) | EGFRSRCKDM4EIDO1TACR1 | |
| SCHEMBL366370 | 0.77 | EGFR (0.43) | EGFRSRCKDM4EIDO1ALDH1A1 | |
| SCHEMBL365470 | 0.76 | EGFR (0.45) | EGFRSRCKDM4EALDH1A1MEN1 | |
| SCHEMBL364264 | 0.75 | MAPT (0.46) | EGFRSRCKDM4EIDO1L3MBTL1 | |
| SCHEMBL366371 | 0.73 | EGFR (0.45) | EGFRSRCPLK1KDM4EL3MBTL1 | |
| SCHEMBL364265 | 0.71 | NR4A2 (0.46) | EGFRSRCKDM4EALDH1A1MEN1 | |
| SCHEMBL1388501 | 0.71 | EGFR (1.00) | EGFRSRCALDH1A1NPC1MEN1 | |
| SCHEMBL20674510 | 0.68 | CNR2 (0.44) | KDM4EALDH1A1KMT2AGAA | |
| SCHEMBL366977 | 0.68 | SCN9A (0.46) | KDM4EALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |