Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.64 |
| ▸ | MEN1 | O00255 | 9/20 | 0.64 |
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | HAT1 | O14929 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL368646 | 0.80 | GAA (0.66) | KMT2AL3MBTL1MEN1MAPTALDH1A1 | |
| SCHEMBL10280819 | 0.78 | GPBAR1 (0.69) | KMT2AL3MBTL1MEN1MAPTALDH1A1 | |
| SCHEMBL368407 | 0.78 | GPBAR1 (0.69) | KMT2AL3MBTL1MEN1MAPTALDH1A1 | |
| SCHEMBL368406 | 0.78 | GPBAR1 (0.69) | KMT2AL3MBTL1MEN1MAPTALDH1A1 | |
| SCHEMBL20869596 | 0.77 | GPR84 (0.73) | KMT2AL3MBTL1MEN1MAPTALDH1A1 | |
| SCHEMBL24145205 | 0.74 | MAPT (0.68) | KMT2AL3MBTL1MEN1MAPTALDH1A1 | |
| SCHEMBL9804914 | 0.74 | MAPT (0.68) | KMT2AL3MBTL1MEN1MAPTALDH1A1 | |
| SCHEMBL2073839 | 0.72 | SLC6A4 (0.66) | KMT2AL3MBTL1MEN1MAPTALDH1A1 | |
| SCHEMBL21399848 | 0.72 | GPR84 (0.59) | KMT2AL3MBTL1MEN1MAPTALDH1A1 | |
| SCHEMBL108954 | 0.70 | GPR84 (0.84) | KMT2AL3MBTL1MEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |