Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.73 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MGAM | O43451 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 6/20 | 0.48 |
| ▸ | SI | P14410 | 6/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108954 | 0.90 | GPR84 (0.84) | GPR84FFAR1CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL29863235 | 0.85 | GPR84 (1.00) | GPR84FFAR1CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL5851244 | 0.85 | GPR84 (1.00) | GPR84FFAR1CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL15731796 | 0.80 | MGAM (0.64) | GPR84FFAR1CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL15709191 | 0.80 | MGAM (0.64) | GPR84FFAR1CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL30919353 | 0.80 | MGAM (0.64) | GPR84FFAR1CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL7290548 | 0.77 | MAPT (0.59) | GPR84FFAR1SLC6A2SLC6A4MEN1 | |
| SCHEMBL30913604 | 0.77 | MAPT (0.59) | GPR84FFAR1SLC6A2SLC6A4MEN1 | |
| SCHEMBL369893 | 0.77 | KMT2A (0.64) | GPR84FFAR1CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL7001304 | 0.76 | GPR84 (0.81) | GPR84FFAR1CYP2D6SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190099453-A1 | MEDICAMENT FOR LIVER REGENERATION AND FOR TREATMENT OF LIVER FAILURE | HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH (DE) | 2019-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190099453-A1 | MEDICAMENT FOR LIVER REGENERATION AND FOR TREATMENT OF LIVER FAILURE | PYGL, HNF4A, ATF1 | GPR84 1048/4885FFAR1 3089/4885CYP2D6 2254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.