Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA6 | P23280 | 4/20 | 0.40 |
| ▸ | CA7 | P43166 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA3 | P07451 | 3/20 | 0.40 |
| ▸ | CA4 | P22748 | 3/20 | 0.40 |
| ▸ | CA5A | P35218 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL6910153 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL16767515 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL11228367 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL8361966 | 0.93 | — | — | |
| Ethylenediamine SCHEMBL3805937 | 0.93 | NFKB1 (0.40) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL11587289 | 0.93 | — | — | |
| Ethylenediamine SCHEMBL8718969 | 0.93 | NFKB1 (0.40) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL7085968 | 0.91 | NFKB1 (0.50) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL3083 | 0.91 | — | — | |
| Ethylenediamine SCHEMBL37647 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4230183-A | CHELATE OF COBALT, NICKEL, IRON, CHROMIUM, OR COPPER | TEXACO INC. (US) | 1980-10-28 | — | — | US | claimed |
| EP-3275539-B1 | HYDROPROCESSING CATALYSTS AND THEIR PRODUCTION | EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY (US) | 2023-04-05 | — | — | EP | disclosed |
| US-20180264450-A1 | HYDROPROCESSING CATALYSTS AND THEIR PRODUCTION | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2018-09-20 | — | — | US | disclosed |
| EP-2576052-B1 | HYDROPROCESSING CATALYSTS AND THEIR PRODUCTION | EXXONMOBIL RES & ENG CO (US) | 2018-07-18 | — | — | EP | disclosed |
| US-10022712-B2 | Hydroprocessing catalysts and their production | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2018-07-17 | — | — | US | disclosed |
| EP-2576053-B1 | HYDROPROCESSING CATALYSTS AND THEIR PRODUCTION | EXXONMOBIL RES & ENG CO (US) | 2018-04-25 | — | — | EP | disclosed |
| EP-3275539-A1 | HYDROPROCESSING CATALYSTS AND THEIR PRODUCTION | ExxonMobil Research and Engineering Company (US) | 2018-01-31 | — | — | EP | disclosed |
| EP-1656332-B1 | METHOD AND SYSTEM FOR TREATING WASTE MATTER FROM ANIMALS CONTAINING UREA | WASTE 2 GREEN LLC (US) | 2017-03-15 | — | — | EP | disclosed |
| WO-2015171277-A1 | HYDROPROCESSING CATALYSTS AND THEIR PRODUCTION | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2015-11-12 | — | — | WO | disclosed |
| US-20140374319-A1 | HYDROPROCESSING CATALYSTS AND THEIR PRODUCTION | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2014-12-25 | — | — | US | disclosed |
| US-4757035-A | Heating modified silazane polymer containing crystallinity increasing amount of iron or copper compound | DOW CORNING CORPORATION (US) | 1988-07-12 | — | — | US | disclosed |
| US-4755496-A | Supported transition metal sulfide promoted molybdenum or tungsten sulfide catalysts and their uses for hydroprocessing | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| US-4698145-A | Supported transition metal sulfide promoted molybdenum or tungsten sulfide catalysts and their uses for hydroprocessing | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1987-10-06 | — | — | US | disclosed |
| US-4654271-A | ORGANIC THIOSULFATE, NICKEL OR COBALT, AMINE | MONSANTO EUROPE, S. A. (BE) | 1987-03-31 | — | — | US | disclosed |
| US-4650563-A | HYDRODENITROGENIZATION, HYDRODESULFURIZATION | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1987-03-17 | — | — | US | disclosed |
| EP-0189634-A1 | Transition metal sulfide promoted molybdenum or tungsten sulfide catalysts and their uses for hydroprocessing | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1986-08-06 | — | — | EP | disclosed |
| EP-0189632-A1 | Supported transition metal sulfide promoted molybdenum or tungsten sulfide catalysts and their uses for hydroprocessing | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1986-08-06 | — | — | EP | disclosed |
| EP-0175384-A2 | Ceramic materials with increased crystallinity from silazane polymers | DOW CORNING CORPORATION (US) | 1986-03-26 | — | — | EP | disclosed |
| EP-0160634-A2 | Metal complexes useful as rubber/metal bonding promoters | MONSANTO EUROPE S.A./N.V. (BE) | 1985-11-06 | — | — | EP | disclosed |
| US-4091822-A | POLYDENTATE AMINE AND ZINC, IRON/II/, COPPER, OR NICKEL, COMPLEXING | LOEWS THEATRES, INC. (US) | 1978-05-30 | — | — | US | disclosed |