⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL8856570 | 0.85 | KDM4E (0.46) | — | |
| SCHEMBL5204640 | 0.80 | — | — | |
| SCHEMBL5158635 | 0.79 | TSHR (0.56) | — | |
| SCHEMBL1171646 | 0.79 | KDM4E (0.54) | — | |
| SCHEMBL18953099 | 0.78 | — | — | |
| SCHEMBL2569547 | 0.78 | — | — | |
| SCHEMBL888653 | 0.78 | — | — | |
| SCHEMBL4591341 | 0.78 | HDAC3 (0.58) | — | |
| SCHEMBL2781925 | 0.78 | KDM4E (0.61) | — | |
| SCHEMBL4591337 | 0.78 | HDAC3 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448909-B | N-carbazolyl-1H-pyrrole-2-carboxamide and application thereof as ligand in copper-catalyzed C-N coupling reaction | 中山大学 | 2023-10-27 | — | — | CN | claimed |
| CN-115448909-A | N-carbazolyl-1H-pyrrole-2-formamide and application thereof as ligand in copper-catalyzed C-N coupling reaction | 中山大学 | 2022-12-09 | — | — | CN | claimed |
| CN-101774874-B | N-arylating method using pyrrole-2-hydrazide compound as ligand in aqueous phase system | UNIV SUN YAT SEN | 2013-05-29 | — | — | CN | claimed |
| CN-101774874-A | N-arylating method using pyrrole-2-hydrazide compound as ligand in aqueous phase system | UNIV SUN YAT SEN | 2010-07-14 | — | — | CN | claimed |
| EP-4658654-A1 | PYRROLO[1,2-D][1,2,4]TRIAZINES AND PYRAZOLO[1,5-D] [1,2,4]TRIAZINES AS NLRP3 INHIBITORS | Janssen Pharmaceutica NV (BE) | 2025-12-10 | — | — | EP | disclosed |
| US-12391781-B2 | Black particles, black coating material, coating film, and black matrix for color filters | SEKISUI CHEMICAL CO., LTD. (JP) | 2025-08-19 | — | — | US | disclosed |
| EP-4063426-B1 | BLACK PARTICLES, BLACK COATING MATERIAL, COATING FILM, AND BLACK MATRIX FOR COLOR FILTERS | SEKISUI CHEMICAL CO LTD (JP) | 2025-06-18 | — | — | EP | disclosed |
| EP-4554945-A1 | PYRROLOTRIAZINE AND IMIDAZOTRIAZINE DERIVATIVES AS MODULATORS OF THE NLRP3 INFLAMMASOME PATHWAY | AC Immune SA (CH) | 2025-05-21 | — | — | EP | disclosed |
| CN-119907802-A | Pyrrolotriazine and imidazotriazine derivatives as modulators of NLRP3 inflammatory small body pathways | AC免疫有限公司 | 2025-04-29 | — | — | CN | disclosed |
| CN-119894897-A | Heteroaromatic compounds for the treatment of neurological disorders | 苏文生命科学有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-119661429-A | Method for preparing pirfenidone through catalysis of oxalyl dihydrazide polymer copper catalyst | 南京工业大学 | 2025-03-21 | — | — | CN | disclosed |
| US-20240398791-A1 | HETEROARYL HETEROCYCLIC COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2024-12-05 | — | — | US | disclosed |
| EP-0566446-A1 | Derivatives of indane-1,3-dione and indane-1,2,3-trione, processes for their preparation and their application in therapy | INNOTHERA (FR) | 1993-10-20 | — | — | EP | disclosed |
| WO-1993020046-A1 | INDAN-1,3-DIONE AND INDAN-1,2,3-TRIONE DERIVATIVES, PROCESSES FOR PREPARATION OF SAME AND THEIR USE AS THERAPEUTIC AGENTS | INNOTHERA (FR) | 1993-10-14 | — | — | WO | disclosed |
| EP-0263071-B1 | 2-Substituted-e-fused-[1,2,4]-triazolo[1,5-c] pyrimidines, pharmaceutical compositions, and uses thereof | CIBA-GEIGY AG (CH) | 1992-08-12 | — | — | EP | disclosed |
| US-4831013-A | BENZODIAZEPINE RECEPTOR ANTAGONISTS | CIBA-GEIGY CORPORATION (US) | 1989-05-16 | — | — | US | disclosed |
| WO-1988002370-A1 | 2-SUBSTITUTED-E-FUSED-[1,2,4]TRIAZOLO[1,5-C]PYRIMIDINES PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | CIBA-GEIGY AG (CH) | 1988-04-07 | — | — | WO | disclosed |
| EP-0263071-A1 | 2-Substituted-e-fused-[1,2,4]-triazolo[1,5-c] pyrimidines, pharmaceutical compositions, and uses thereof | CIBA-GEIGY AG (CH) | 1988-04-06 | — | — | EP | disclosed |
| US-4713383-A | ADENOSINE AND BENZODIAZEPINE ANTAGONISTS | CIBA-GEIGY CORPORATION (US) | 1987-12-15 | — | — | US | disclosed |
| EP-0181282-A1 | Triazoloquinazoline compounds | CIBA-GEIGY AG (CH) | 1986-05-14 | — | — | EP | disclosed |