⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3699321 | 0.80 | — | — | |
| SCHEMBL18953099 | 0.80 | — | — | |
| SCHEMBL888653 | 0.80 | — | — | |
| SCHEMBL2569547 | 0.80 | — | — | |
| SCHEMBL31688426 | 0.78 | KDM4E (0.51) | — | |
| SCHEMBL28029054 | 0.78 | — | — | |
| SCHEMBL6917461 | 0.77 | KDM4E (0.69) | — | |
| SCHEMBL3248130 | 0.77 | ATM (0.49) | — | |
| SCHEMBL371069 | 0.75 | TSHR (0.54) | — | |
| SCHEMBL5320628 | 0.75 | TSHR (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368150-B | Hydroxamic acid triterpenoid derivative | 维瓦赛尔生物技术西班牙有限公司 | 2022-02-25 | — | — | CN | claimed |
| US-20230056785-A1 | GAS-STORING MATERIAL INCLUDING METAL/ORGANIC FRAMEWORK BONDED BY HYDROXAMIC ACID | RIKKYO EDUCATIONAL CORPORATION (JP) | 2023-02-23 | — | — | US | disclosed |
| CN-108368150-B | Hydroxamic acid triterpenoid derivative | 维瓦赛尔生物技术西班牙有限公司 | 2022-02-25 | — | — | CN | disclosed |
| EP-1539744-A4 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARM INC (US) | 2007-06-06 | — | — | EP | disclosed |
| EP-1539744-A2 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | Vicuron Pharmaceuticals, Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2005011675-A1 | DERIVATIVES OF 3-HYDROXY-PYRROLE-2,4-DICARBOXYLIC ACID AND USES THEREOF | AVALON PHARMACEUTICALS (US) | 2005-02-10 | — | — | WO | disclosed |
| US-20040146941-A1 | Chemical encoding technology for combinatorial synthesis | MASSACHUSETTS, UNIVERSITY OF | 2004-07-29 | — | — | US | disclosed |
| WO-2004041752-A2 | CHEMICAL ENCODING TECHNOLOGY FOR COMBINATORIAL SYNTHESIS | UNIVERSITY OF MASSACHUSETTS (US) | 2004-05-21 | — | — | WO | disclosed |
| WO-2004007444-A2 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS, INC. (US) | 2004-01-22 | — | — | WO | disclosed |
| CN-1423638-A | Oxazolyl hydroxamic acids as procollagen C-protease inhibitors | PFIZER LTD (US) | 2003-06-11 | — | — | CN | disclosed |