⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28029054 | 0.98 | — | — | |
| SCHEMBL14742539 | 0.88 | KDM4E (0.44) | — | |
| Edetic Acid SCHEMBL7538782 | 0.82 | TSHR (0.44) | — | |
| SCHEMBL5204640 | 0.80 | — | — | |
| 1-Methylimidazole SCHEMBL6040916 | 0.80 | CD38 (0.42) | — | |
| SCHEMBL3699321 | 0.78 | — | — | |
| SCHEMBL2569547 | 0.78 | — | — | |
| SCHEMBL18953099 | 0.78 | — | — | |
| SCHEMBL161785 | 0.78 | KDM4E (0.49) | — | |
| SCHEMBL2449027 | 0.78 | KDM4E (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682135-B2 | Drug delivery product and methods | UNIVERSITY OF MASSACHUSETTS (US) | 2017-06-20 | — | — | US | claimed |
| US-9382197-B2 | Substituted hydroxamic acids and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2016-07-05 | — | — | US | claimed |
| US-20140335047-A1 | DRUG DELIVERY PRODUCT AND METHODS | UNIVERSITY OF MASSACHUSETTS (US) | 2014-11-13 | — | — | US | claimed |
| US-8546588-B2 | Substituted hydroxamic acids and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-10-01 | — | — | US | claimed |
| EP-1755567-B1 | DRUG DELIVERY PRODUCT AND METHODS | UNIV MASSACHUSETTS (US) | 2010-11-03 | — | — | EP | claimed |
| CN-101001615-A | Drug delivery product and method | NEXMED HOLDINGS INC (US) | 2007-07-18 | — | — | CN | claimed |
| US-20070054276-A1 | Polynucleotide analysis and methods of using nanopores | AGILENT TECHNOLOGIES, INC. | 2007-03-08 | — | — | US | claimed |
| EP-1755567-A2 | DRUG DELIVERY PRODUCT AND METHODS | Nexmed Holdings, Inc. (US) | 2007-02-28 | — | — | EP | claimed |
| CN-1267419-C | Trifluoromethylpyrrole carboxamides and trifluoromethylpyrrolethionamides as fungicides | SYNGENTA PARTICIPATIONS AG (CH) | 2006-08-02 | — | — | CN | claimed |
| WO-2006007372-A2 | DRUG DELIVERY PRODUCT AND METHODS | OSTROFF GARY R (US) | 2006-01-19 | — | — | WO | claimed |
| US-20030211508-A1 | Charged compounds comprising a nucleic acid binding moiety and uses therefor | GENESOFT, INC. | 2003-11-13 | — | — | US | claimed |
| EP-1265921-A1 | CHARGED COMPOUNDS COMPRISING A NUCLEIC ACID BINDING MOIETY AND USES THEREFOR | Genesoft, Inc. (US) | 2002-12-18 | — | — | EP | claimed |
| US-20020065227-A1 | Charged compounds comprising a nucleic acid binding moiety and uses therefor | GENESOFT PHARMACEUTICALS, INC. | 2002-05-30 | — | — | US | claimed |
| WO-2001074898-A2 | CHARGED COMPOUNDS COMPRISING A NUCLEIC ACID BINDING MOIETY AND USES THEREFOR | GENESOFT, INC. (US) | 2001-10-11 | — | — | WO | claimed |
| CN-1311774-A | Trifluoromethyl pyrrole carboxamides | SINGENTA INVOLVEMENT CO LTD (CH) | 2001-09-05 | — | — | CN | claimed |
| US-6090947-A | Method for the synthesis of pyrrole and imidazole carboxamides on a solid support | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2000-07-18 | — | — | US | claimed |
| EP-0986539-A1 | DNA-BINDING PYRROLE AND IMIDAZOLE POLYAMIDE DERIVATIVES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2000-03-22 | — | — | EP | claimed |
| US-5955590-A | OLIGONUCLEOTIDE COVALENTLY COUPLED TO PEPTIDE OF N-METHYLPYRROLECARBOXAMIDES; FOR STABILIZING HYBRIDIZATION COMPLEXES IN ANTISENSE THERAPY AND DNA DETECTION SYSTEMS USING PROBES | WORCESTER FOUNDATION FOR BIOMEDICAL RESEARCH (US) | 1999-09-21 | — | — | US | claimed |
| WO-1998049142-A1 | DNA-BINDING PYRROLE AND IMIDAZOLE POLYAMIDE DERIVATIVES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-11-05 | — | — | WO | claimed |
| WO-1998002448-A1 | CONJUGATES OF MINOR GROOVE DNA BINDERS WITH ANTISENSE OLIGONUCLEOTIDES | UNIVERSITY OF MASSACHUSETTS (US) | 1998-01-22 | — | — | WO | claimed |