Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3695064 | 0.95 | PTPN1 (0.51) | PTPN1CA2CA1CYP1A2GABRA1 | |
| SCHEMBL3699504 | 0.86 | PTPN1 (0.48) | PTPN1CA2CA1CYP1A2GABRA1 | |
| SCHEMBL3705368 | 0.84 | CA2 (0.48) | PTPN1CA2CA1CYP1A2CYP2C9 | |
| SCHEMBL3689674 | 0.84 | TDP2 (0.44) | PTPN1CA2CA1CYP1A2CYP2C9 | |
| SCHEMBL6841055 | 0.83 | PTPN1 (0.48) | PTPN1CA2CA1CYP1A2GABRA1 | |
| SCHEMBL3692363 | 0.83 | PTPN1 (0.45) | PTPN1CA2CA1CYP1A2GABRA1 | |
| SCHEMBL3695040 | 0.83 | PTPN1 (0.62) | PTPN1CA2CA1CYP1A2CYP2C9 | |
| SCHEMBL3694663 | 0.82 | CA2 (0.46) | PTPN1CA2CA1CYP1A2CYP2C9 | |
| SCHEMBL3688310 | 0.80 | CA2 (0.50) | PTPN1CA2CA1CYP1A2CYP2C9 | |
| SCHEMBL3698561 | 0.78 | TDP2 (0.44) | PTPN1CA2CA1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8241855-B2 | Method for detecting cytosine methylations | EPIGENOMICS AG (DE) | 2012-08-14 | — | — | US | claimed |
| EP-1976498-A2 | CHEMICAL COMPOUNDS | SmithKline Beecham Corporation (US) | 2008-10-08 | — | — | EP | claimed |
| WO-2007127505-A2 | USE OF SULFONAMIDE DERIVATIVES IN THE TREATMENT OF DISORDERS OF THE METABOLISM AND THE NERVOUS SYSTEM | SMITHKLINE BEECHAM CORPORATION (US) | 2007-11-08 | — | — | WO | claimed |
| EP-1325154-B1 | METHOD FOR THE DETECTION OF CYTOSINE METHYLATIONS | EPIGENOMICS AG (DE) | 2007-08-01 | — | — | EP | claimed |
| US-7118868-B2 | Method for detecting cytosine methylations | EPIGENOMICS AG (DE) | 2006-10-10 | — | — | US | claimed |
| EP-1707642-A2 | Method for detecting cytosine methylations | Epigenomics AG (DE) | 2006-10-04 | — | — | EP | claimed |
| EP-1294945-B1 | METHOD FOR DETECTING CYTOSINE METHYLATIONS | EPIGENOMICS AG (DE) | 2006-08-30 | — | — | EP | claimed |
| US-20040152080-A1 | Method for detecting cytosine methylations | QIAGEN GMBH (DE) | 2004-08-05 | — | — | US | claimed |
| US-8377638-B2 | Process for the detection of cytosine methylations | QIAGEN GMBH (DE) | 2013-02-19 | — | — | US | disclosed |
| US-8241855-B2 | Method for detecting cytosine methylations | EPIGENOMICS AG (DE) | 2012-08-14 | — | — | US | disclosed |
| US-20100297614-A1 | PROCESS FOR THE DETECTION OF CYTOSINE METHYLATIONS | QIAGEN GMBH (DE) | 2010-11-25 | — | — | US | disclosed |
| EP-1977011-B1 | PROCESS FOR THE DETECTION OF CYTOSINE METHYLATIONS | QIAGEN GMBH (DE) | 2010-07-28 | — | — | EP | disclosed |
| EP-1976498-A2 | CHEMICAL COMPOUNDS | SmithKline Beecham Corporation (US) | 2008-10-08 | — | — | EP | disclosed |
| EP-1977011-A1 | PROCESS FOR THE DETECTION OF CYTOSINE METHYLATIONS | Qiagen GmbH (DE) | 2008-10-08 | — | — | EP | disclosed |
| EP-1325154-B1 | METHOD FOR THE DETECTION OF CYTOSINE METHYLATIONS | EPIGENOMICS AG (DE) | 2007-08-01 | — | — | EP | disclosed |
| WO-2007077262-A1 | PROCESS FOR THE DETECTION OF CYTOSINE METHYLATIONS | QIAGEN GMBH (DE) | 2007-07-12 | — | — | WO | disclosed |
| US-7118868-B2 | Method for detecting cytosine methylations | EPIGENOMICS AG (DE) | 2006-10-10 | — | — | US | disclosed |
| EP-1707642-A2 | Method for detecting cytosine methylations | Epigenomics AG (DE) | 2006-10-04 | — | — | EP | disclosed |
| EP-1294945-B1 | METHOD FOR DETECTING CYTOSINE METHYLATIONS | EPIGENOMICS AG (DE) | 2006-08-30 | — | — | EP | disclosed |
| US-20040152080-A1 | Method for detecting cytosine methylations | QIAGEN GMBH (DE) | 2004-08-05 | — | — | US | disclosed |