Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 6/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3695803 | 0.94 | FPR1 (0.38) | FPR1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL3808568 | 0.94 | FPR1 (0.39) | FPR1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL4566346 | 0.90 | FPR1 (0.38) | FPR1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL3701317 | 0.89 | FPR1 (0.38) | FPR1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL3693159 | 0.89 | FPR1 (0.42) | FPR1ABCC9ABCC8KCNJ11KCNJ8 | |
| Hydrochloric Acid SCHEMBL3707038 | 0.89 | FPR1 (0.36) | FPR1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL3705290 | 0.86 | FPR1 (0.41) | FPR1ABCC9ABCC8KCNJ11KCNJ8 | |
| Fumaric Acid SCHEMBL3705163 | 0.85 | FPR1 (0.33) | FPR1ABCC9ABCC8KCNJ11KCNJ8 | |
| Fumaric Acid SCHEMBL3705157 | 0.85 | FPR1 (0.33) | FPR1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL3697138 | 0.85 | SLC16A3 (0.34) | ABCC9ABCC8KCNJ11KCNJ8CACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009041705-A9 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2009-08-13 | — | — | WO | disclosed |
| WO-2009041705-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-02 | — | — | WO | disclosed |