Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 2/20 | 0.42 |
| ▸ | CCR8 | P51685 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | PARP16 | Q8N5Y8 | 2/20 | 0.39 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8796079 | 0.82 | ALDH1A1 (0.38) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL28168522 | 0.78 | NPC1 (0.47) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL12143649 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL27921494 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL24867570 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL24868506 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL19013047 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL899802 | 0.78 | NPC1 (0.47) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL20495641 | 0.75 | MAOB (0.47) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL27940047 | 0.75 | PDE10A (0.40) | ALDH1A1MAPTNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104870422-A | Novel amine derivative or salt thereof | TOYAMA CHEMICAL CO LTD | 2015-08-26 | — | — | CN | disclosed |
| EP-2593432-B1 | N-SULFONYLBENZAMIDE DERIVATIVES USEFUL AS VOLTAGE GATED SODIUM CHANNEL INHIBITORS | PFIZER LTD (GB) | 2014-10-22 | — | — | EP | disclosed |
| EP-2593433-A2 | N-SULFONYLBENZAMIDES AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | Pfizer Limited (GB) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007877-A2 | CHEMICAL COMPOUNDS | PFIZER LIMITED (GB) | 2012-01-19 | — | — | WO | disclosed |