Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4132219 | 0.86 | DYRK1A (0.33) | DYRK1AFFAR4 | |
| SCHEMBL3650568 | 0.85 | CTSD (0.32) | — | |
| SCHEMBL3652579 | 0.85 | PPARG (0.32) | DYRK1AFFAR4 | |
| SCHEMBL3806866 | 0.85 | GPBAR1 (0.30) | DYRK1AFFAR4 | |
| SCHEMBL3654415 | 0.84 | MGAM (0.33) | — | |
| SCHEMBL4023653 | 0.83 | — | — | |
| SCHEMBL3700377 | 0.82 | PDK2 (0.34) | DYRK1AFFAR4 | |
| SCHEMBL3804241 | 0.82 | ALDH1A1 (0.32) | — | |
| SCHEMBL3690491 | 0.80 | FFAR4 (0.32) | FFAR4 | |
| SCHEMBL3700382 | 0.79 | DYRK1A (0.35) | DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009041705-A9 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2009-08-13 | — | — | WO | disclosed |
| WO-2009041705-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-02 | — | — | WO | disclosed |