Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.53 |
| ▸ | SCD | O00767 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1906427 | 0.87 | MIF (0.62) | HDAC1CYP19A1HSP90AB1SCD | |
| SCHEMBL15671558 | 0.85 | HDAC1 (0.52) | HDAC1CYP19A1NPC1RAB9AHSP90AB1 | |
| SCHEMBL11420125 | 0.81 | HDAC1 (0.54) | HDAC1CYP19A1NPC1RAB9AHSP90AB1 | |
| SCHEMBL12994253 | 0.81 | PPID (0.62) | HDAC1CYP19A1ALDH1A1LMNA | |
| SCHEMBL24665771 | 0.80 | CYP19A1 (0.60) | HDAC1CYP19A1NPC1RAB9AHSP90AB1 | |
| SCHEMBL31438177 | 0.80 | KLKB1 (0.52) | HDAC1CYP19A1SCDALDH1A1LMNA | |
| SCHEMBL15336924 | 0.80 | HDAC1 (0.55) | HDAC1CYP19A1NPC1RAB9AHSP90AB1 | |
| SCHEMBL13269943 | 0.80 | FAAH (0.43) | HDAC1 | |
| SCHEMBL31438183 | 0.79 | KDM5B (0.51) | HDAC1SCDLMNA | |
| SCHEMBL31256659 | 0.79 | CYP19A1 (0.59) | HDAC1CYP19A1NPC1RAB9AHSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8618162-B2 | Insecticidal carbamates exhibiting species-selective inhibition of acetylcholinesterase (AChE) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2013-12-31 | — | — | US | disclosed |
| US-20120122970-A1 | INSECTICIDAL CARBAMATES EXHIBITING SPECIES-SELECTIVE INHIBITION OF ACETYLCHOLINESTERASE (AChE) | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122970-A1 | INSECTICIDAL CARBAMATES EXHIBITING SPECIES-SELECTIVE INHIBITION OF ACETYLCHOLINESTERASE (AChE) | ACHE, BCHE, CHAT | HDAC1 294/4885CYP19A1 76/4885NPC1 953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.