Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.46 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.40 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.40 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.40 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12505702 | 0.78 | NAPRT (0.46) | NAPRTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL12505695 | 0.77 | SLC5A1 (0.52) | SLC5A1SLC5A2L3MBTL1TDP1CYP19A1 | |
| SCHEMBL3403133 | 0.74 | NAPRT (0.60) | NAPRTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL30995645 | 0.73 | NAPRT (0.50) | NAPRTNPC1RAB9AALDH1A1FFAR1 | |
| SCHEMBL12505692 | 0.72 | SLC5A1 (0.44) | SLC5A1SLC5A2L3MBTL1TDP1CYP19A1 | |
| SCHEMBL2230843 | 0.71 | NAPRT (0.60) | NAPRTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL4940823 | 0.70 | KMT2A (0.62) | SLC5A1SLC5A2NPC1RAB9AL3MBTL1 | |
| SCHEMBL9121060 | 0.69 | L3MBTL1 (0.62) | SLC5A1SLC5A2NPC1RAB9AL3MBTL1 | |
| SCHEMBL28022706 | 0.69 | TDP1 (0.53) | NPC1RAB9AL3MBTL1TDP1CYP19A1 | |
| SCHEMBL3182033 | 0.68 | NAPRT (0.67) | NAPRTNPC1RAB9AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |