Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | BRS3 | P32247 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.47 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.47 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.47 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.47 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.47 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28023427 | 0.89 | GPR52 (0.56) | FFAR1ABCB1LTB4R2GPR52ALDH1A1 | |
| SCHEMBL28022725 | 0.85 | SLC6A4 (0.51) | L3MBTL1FFAR1FFAR4BRS3LTB4R2 | |
| SCHEMBL9356318 | 0.80 | KMT2A (0.47) | TDP1L3MBTL1FFAR1FFAR4BRS3 | |
| SCHEMBL9542216 | 0.79 | L3MBTL1 (0.46) | TDP1L3MBTL1BRS3LTB4R2ALDH1A1 | |
| SCHEMBL9024443 | 0.78 | GSK3B (0.52) | TDP1L3MBTL1BRS3LTB4R2ALDH1A1 | |
| SCHEMBL12330301 | 0.77 | NPC1 (0.70) | TDP1L3MBTL1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL27889179 | 0.77 | RECQL (0.62) | L3MBTL1ABCB1GPR52ALDH1A1KMT2A | |
| SCHEMBL372 | 0.77 | KMT2A (0.60) | BRS3LTB4R2ALDH1A1MEN1KMT2A | |
| SCHEMBL31402608 | 0.77 | KMT2A (0.60) | BRS3LTB4R2ALDH1A1MEN1KMT2A | |
| SCHEMBL28022702 | 0.76 | HCAR2 (0.56) | TDP1L3MBTL1FFAR1FFAR4BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104860803-B | Biphenyl ketonic compound and its preparation method and application | 暨南大学 | 2016-11-30 | — | — | CN | disclosed |
| CN-104860803-A | Biphenyl compound and preparation method and application thereof | UNIV JINAN | 2015-08-26 | — | — | CN | disclosed |